| 穴位埋线对慢性应激雌性大鼠下丘脑-垂体-性腺轴的影响 |
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| 引用本文： | 徐朝霞,张宏,谭少明,边心会,范春. 穴位埋线对慢性应激雌性大鼠下丘脑-垂体-性腺轴的影响[J]. 上海针灸杂志, 2009, 28(1): 54-56 |
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| 作者姓名： | 徐朝霞 张宏 谭少明 边心会 范春 |
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| 作者单位： | 广州中医药大学,广东,510405;广州中医药大学,广东,510405;广州中医药大学,广东,510405;广州中医药大学,广东,510405;广州中医药大学,广东,510405 |
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| 基金项目： | 广东省中医药管理局课题 |
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| 摘 要： | 目的探讨穴位埋线对慢性应激模型大鼠下丘脑-垂体-性腺轴（HPG轴）的调节作用。方法采用制动应激方式作用于雌性SD大鼠21天,制成慢性应激模型,在百会、内关、三阴交、太冲穴进行穴位埋线,每5天1次,共埋线4次。运用放射免疫法（RIA）检测大鼠下丘脑GnRH、血清LH、E2和Cor的含量,并与对照组、模型组做比较。结果模型组大鼠下丘脑GnRH、血清LH和血清＆的含量明显低于对照组（P〈0．05）;埋线组下丘脑GnRH、血清LH和血清E。的含量明显高于模型组（P〈0．05）,与对照组比较差异无统计学意义（P〉0．05）。模型组大鼠血清Cor含量明显高于对照组（P〈0．05）：埋线组血清中Cor含量明显低于模型组（P〈0．01）,与对照组比较差异无统计学意义（P〉0．05）。结论慢性应激引起雌性大鼠HPG轴受到抑制,穴位埋线可以减轻应激对HPG轴的抑制作用。
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| 关 键 词： | 应激 埋线 下丘脑-垂体-性腺轴 糖皮质激素 |
Influence of Acupoint Catgut-embedding Therapy on the Hypothalamus-pituitary-gonad Axis in Female Chronic Stress Rats |
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| XU Zhao-xia,ZHANG Hong,TAN Shao-ming,BIAN Xin-hui,FAN Chun. Influence of Acupoint Catgut-embedding Therapy on the Hypothalamus-pituitary-gonad Axis in Female Chronic Stress Rats[J]. Shanghai Journal of Acupuncture and Moxibustion, 2009, 28(1): 54-56 |
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| Authors: | XU Zhao-xia ZHANG Hong TAN Shao-ming BIAN Xin-hui FAN Chun |
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| Affiliation: | XU Zhao-xia,ZHANG Hong,TAN Shao-ming,BIAN Xin-hui,FAN Chun.Guangzhou University of traditional Chinese medicine,Guangzhou 510405,China |
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| Abstract: | Objective To investigate the regulative effect of acupoint catgut-embedding therapy on the hypothalamus-pituitary-gonad axis in a rat model of chronic stress.Methods Female SD rats were treated by immobilization stress for 21 days to make a model of chronic stress.Catgut was embedded at points Baihui(GV20), neiguan(PC6), sanyinjiao(SP6) and taichong(LR3) once every five days for 4 times.Rat hypothalamic GnRH and serum LH, E2 and Cor contents were measured by radioimmunoassay.A comparison was made with the c... |
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| Keywords: | Stress Catgut-embedding therapy Hypothalamus-pituitary-gonad axis Glucocorticoid |
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