| 参附脱毒胶囊Ⅱ期临床110例双盲评估研究 |
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| 引用本文： | 张锐敏,李吉祥,孙新会,郑玲,杨丽萍,张杰,李建华,马克坚,袁小波,万文鹏.参附脱毒胶囊Ⅱ期临床110例双盲评估研究[J].中国药物依赖性杂志,2002,11(3):197-201,232. |
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| 作者姓名： | 张锐敏 李吉祥 孙新会 郑玲 杨丽萍 张杰 李建华 马克坚 袁小波 万文鹏 |
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| 作者单位： | 云南省药物依赖防治研究所,昆明,650228 |
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| 摘 要： | 目的··:评价参附脱毒胶囊用于阿片类依赖者脱毒治疗的疗效及不良反应。方法··:110例随机双盲对照试验设计 ,对照药为盐酸可乐定 ,其中参附脱毒胶囊组80例 ,可乐定组30例。结果··:参附脱毒胶囊控制戒断症状的作用与可乐定相同 (P>0.05) ,控制典型戒断症状 (如骨肌肉痛 )优于可乐定 (P<0.05)。结论··:参附脱毒胶囊用于阿片类依赖的脱毒治疗疗效肯定 ,安全可靠 ,无严重不良反应。
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| 关 键 词： | 参附脱毒胶囊 可乐定 海洛因依赖 戒断症状 不良反应 |
A DOUBLE- BLIND CLINICAL TRIAL OF SHENGFUTUODU CAPSULE IN THE TREATMENT OF HEROIN WITHDRAWAL SYMPTOMS |
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| Abstract: | Objective: To evaluate the effect and safety of Shenfutuodu capsule, a traditional Chinese medicine, on alleviating opiate withdrawal symptoms in heroin addicts. Methods: A randomized, double-blind trial was carried out in 110 heroin addicts. They had been treated for 10 days. Results: In Shenfutudu group, the alleviation of withdrawal symptoms was similar to that in Clonidine group, and the effect of relieving pain was better than clonidine. Conclusion: Shenfutudu capsule is effective in the treatment of opiate withdrawal symptoms without serious side effects. |
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