| 氧化苦参碱对人胃癌SGC-7901细胞株生长的影响 |
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| 引用本文： | 闵光涛 曹农 杨伟林 李玉民. 氧化苦参碱对人胃癌SGC-7901细胞株生长的影响[J]. 中华现代外科学杂志, 2005, 2(21): 1931-1932 |
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| 作者姓名： | 闵光涛 曹农 杨伟林 李玉民 |
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| 作者单位： | 兰州大学第一医院普外科,甘肃兰州730000 |
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| 基金项目： | 中组部、中科院“西部之光”人才培养计划资助项目（编号：20000132） |
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| 摘 要： | 目的观察氧化苦参碱对人胃癌SGC-7901细胞株体外增殖率的影响情况。方法噻唑蓝（MTT）比色测定法确定氧化苦参碱对胃癌SGC-7901细胞存活抑制作用。结果试验浓度下氧化苦参碱对SGC-7901细胞增殖抑制作用呈剂量依赖性，当浓度为12mg／ml时，对SGC-7901增殖的抑制率最大，达到87．63％。结论氧化苦参碱对人胃癌SGC-7901细胞的增殖具有明显的抑制作用。
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| 关 键 词： | 胃癌 氧化苦参碱 SGC-7901细胞株 体外增殖率 |
| 文章编号： | 1681-102X（2005）21-1931-02 |
| 收稿时间： | 2005-11-20 |
The inhibition on oxymatrine to SGC -7901 cell line determined by MTT colorimetric assay |
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| MIN Guang - tao, CAO Nong, YANG Wei - lin,et al.. The inhibition on oxymatrine to SGC -7901 cell line determined by MTT colorimetric assay[J]. , 2005, 2(21): 1931-1932 |
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| Authors: | MIN Guang - tao CAO Nong YANG Wei - lin et al. |
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| Affiliation: | MIN Guang - tao, CAO Nong, YANG Wei - lin, et al. |
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| Abstract: | Objective The role of oxymatrine to the proliferation rate of SGC - 7901 cell line in vitro was observed. Methods The inhibition of SGC - 7901 was determined by MTT eolorimetrie assay. Results The proliferation of SGC - 7901 was obviously inhibited by oxymatrine in a dose dependent manner. The inhibitory rate came to the peak at 87.63% ,when cultured with matrine at 12mg/ml. Conclusion Oxymatrine can significantly inhibit the proliferation of SGC -7901 cell. |
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| Keywords: | gastric carcinoma oxymatrine SGC - 7901 cell line proliferation rate in vitro |
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