| Effects of Astragalus membranaceus in Promoting T-helper Cell Type 1 Polarization and Interferon-γ Production by Up-regulating T-bet Expression in Patients with Asthma |
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| 作者姓名： | 王刚 刘春涛 王曾礼 颜存粮 罗凤鸣 王蕾 李廷谦 |
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| 作者单位： | Department of Integrated Traditional Chinese and Western Medicine West China Hospital Sichuan University Chengdu (610041)，Department of Respiratory Disease West China Hospital Sichuan University，Department of Respiratory Disease West China Hospital Sichuan University，Department of Laboratory Medicine Shenzhen Hospital Affiliated to Peking University，Department of Respiratory Disease West China Hospital Sichuan University，Department of Integrated Traditional Chinese and Western Medicine West China Hospital Sichuan University Chengdu (610041)，Department of Integrated Traditional Chinese and Western Medicine West China Hospital Sichuan University Chengdu (610041) |
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| 基金项目： | *Supported by Science Foundation of State Administration of Traditional Chinese Medicine (No. 04-05JQ03), and partly supported by China Postdoctoral Science Foundation (No. 2005037800). |
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| 摘 要： | ![]()
Asthma is a clinical syndrome character-ized by intermittent episodes of wheezing andcoughing,and associated closely with reversibleairway obstruction,airway inflammation,airwayhyper-responsiveness(AHR),and airway re-modeling.In asthma,the polarized T lympho-cyte response and enhanced secretion of cyto-kines got involved in the regulation of immuno-globin E(IgE),mast cells,basophils,and eo-sinophils,ultimately leading to airway inflam-mation(1).The pro-inflammatory cytokines pro-duced by Tc…
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