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| 小儿特发性IgM肾病与微小病变肾病综合征的临床病理研究 | |
| 引用本文： | 马恒颢 庄昭勤. 小儿特发性IgM肾病与微小病变肾病综合征的临床病理研究[J]. 中华肾脏病杂志, 1994, 10(1): 8-11 |
| 作者姓名： | 马恒颢 庄昭勤 |
| 作者单位： | 广州军区总医院儿科 |
| 摘 要： | 对于ＩｇＭ在肾小球系膜区沉积的临床和病理意义争论颇多，我们就２５例ＩｇＭ肾病（ＩｇＭＮ）与１６例微小病变肾病（ＭＣＮＳ）患儿的临床与病理进行对比分析，结果表明ＩｇＭＮ与ＭＣＮＳ临床表现极为相似。但ＩｇＭＮ对肾上腺皮激素治疗反应不佳，且易反复或复发。这可能与ＩｇＭＮ的病理改变较重有关。另外作者还对ＩｇＭ在系膜区沉积潜在临床与病理意义进行了初步探讨，认为ＩｇＭ在系膜区沉积无明确的临床和病理意义。 |
| 关 键 词： | IgM肾病 微小病变 肾病综合征 |
THE CLINICAL AND PATHOLOGICALSTUDY OF IgM NEPHROPATHY AND MINI-MAL CHANGE DISEASE NEPHROTIC SYNDR-OME IN CHILDREN |
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| Ma Henghao,ZhuangZhaoqin,Xie Xtangao, Shao Yuzhen.. THE CLINICAL AND PATHOLOGICALSTUDY OF IgM NEPHROPATHY AND MINI-MAL CHANGE DISEASE NEPHROTIC SYNDR-OME IN CHILDREN[J]. Chinese Journal of Nephrology, 1994, 10(1): 8-11 | |
| Authors: | Ma Henghao ZhuangZhaoqin Xie Xtangao Shao Yuzhen. |
| Affiliation: | PediatricDept. Guangzhou General Hospital of PLA |
| Abstract: | cliulcal and pathological comparisonstduy was made between 25 cases of IgM ne-phropathy (IgMN) and 16 cases of minimalchange disease nephrotic syndrome (MCDNS)in children. The results demonstrated that theclinical manifestation was similar in IgMNand MCDNS. The IgMN, however, responsedpoorly to steroid and was easy to relapse. Itprobably related to more serious change of pa-thology in IgMN. In addition, ure had prelim-inarily studied the potential significance ofIgM deposition in mesangial area. We coasi-dered that the deposition of IgM had no definiteclinical and pathological meaning. |
| Keywords: | Nephrotic Syndrome IgMNephropathy Minimal Change Disease. |
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