定量组织速度成像测定二尖瓣环运动速度对尿毒症患者左心舒张功能的评价

目的应用定量组织速度成像(QTVI)测定二尖瓣环运动速度评价尿毒症病患者左室舒张功能。方法应用定量组织速度成像测定30例正常人和32例尿毒症患者的二尖瓣环舒张早期峰值速度(Ve)、左房收缩期峰值速度(Va),计算Ve/Va比值;并用脉冲多普勒测定二尖瓣口舒张早期峰值血流速度E峰、舒张晚期峰值血流速度A峰,计算E/A值。结果正常组舒张早期峰值速度(E)>左房收缩期峰值速度(A),E/A>1;二尖瓣环舒张早期峰值速度(Ve)>左房收缩期峰值速度(Va),Ve/Va>1,正常组与尿毒症患者组二尖瓣口血流频谱及二尖瓣环运动组织速度成像测值有显著性差异,尿毒症患者组中二尖瓣环运动速度Ve/Va与二尖瓣血流频谱V/A无显著性差异。但在检出病例数中QTVI阳性例数明显高于血流频谱。结论应用定量组织速度成像测定二尖瓣口运动速度能较准确估计尿毒症患者左室舒张功能。

Assessment of Left Ventricular Diastolic Function in Patients with Uremia Using Quantitative Tissue Velocity Imaging

Objective To assess the left ventricular diastolic function in uremic patients using mitral annulus velocity determined by quantitative tissue velocity imaging(QTVI).Methods Thirty normal subjects and 32 uremic patients were studied.The mitral annulus velocities during early diastole(Ve),atrial contraction(Va) were measured by QTVI,and Ve/Va was calculated.The blood flow velocity of mitral annalus during early diastole(E) and atrial contraction(A) were also measured by pulsed Doppler echocardiography and E/A ratio was calculated.Results There were significant difference in measuring values between normal subjects and uremic patients.There was no significant difference between Ve/Va of the mitral annulus and E/A ratio in uremic patiengs,but positive cases were found by QTVI more than that by pulsed Doppler echocardiography.Conclusions The mitral annular velocity determined by QTVI can accurately evaluate the left ventricular diastolic function in uremic patients.