肌萎缩侧索硬化患者焦虑和抑郁状况及其影响因素调查

目的了解肌萎缩侧索硬化(amyotrophic lateral sclerosis,ALS)患者焦虑、抑郁状况及其影响因素。方法采用Zung编制的焦虑自评量表(self-rating anxiety scale,SAS)、抑郁自评量表(self-rating depression scale,SDS),对174例ALS患者进行调查。了解ALS患者焦虑、抑郁状况及其影响因素。结果 174例患者中,发生焦虑21例,占12.07%;发生抑郁65例,占37.36%。患者SAS、SDS得分均高于全国常模,组间比较,均P0.001,差异具有统计学意义。女性患者抑郁发生率较男性患者高(P0.05)。结论 ALS患者焦虑、抑郁心理问题较正常人更为突出,治疗过程中要重视对患者的心理支持和疏导,特别应关注女性患者的心理健康状况。

Anxiety and depression of patients with amyotrophic lateral sclerosis

Objective To study the anxiety and depression in patients with amyotrophic lateral sclerosis（ALS）.Method One hundred and seventy-four ALS patients were evaluated by self-rating anxiety scale（SAS）and self-rating depression scale（SDS） to study the anxiety and depression in them.Results In 174 ALS patients,21 had anxiety（12.07%）and 65 the depression（37.36%）. The scores of SAS and SDS in the ALS patients were significantly higher than the national norm（P〈0.05）.The depression incidence in the female patients was significantly higher than the male（P〈0.05）.Conclusions Anxiety and depression are more severe than those in ALS patients than those in normal people.Psychological support is important for these patients,especially for those female patients.