注射用头孢呋辛钠与4种药物配伍的稳定性

目的：研究注射用头孢呋辛钠与注射用穿琥宁、葛根素注射液、氨甲苯酸注射液、酚磺乙胺注射液在0．95氯化钠输液中配伍的稳定性。方法：采用紫外分光光度法考察各混合液室温条件下（15－25℃）配伍后0－6h内含量的变化，同时观察PH值及外观的变化，结果：头孢呋辛钠与葛根素配伍后含量及外观稳定，但PH值有变化；与酚磺乙胺、穿琥宁、氨甲苯配伍后含量，外观、PH值均稳定。结论：头孢呋辛钠可与酚磺乙胺、穿琥宁、氨甲苯酸在0．9％氯化钠输液中配伍应用，但与葛素配伍应用则不妥。

Study on the Compatibility of Cefuroxime Sodium Injection with Other Four Drugs

Objectives: To study the compatibility of cefuroxime sodium injection with Chuanhuning injection, puerarin injection, p-aminomethylbenzoic acid injection, and elamsilate injection in 0.9 % sodium chloride injection. Methods: Ultraviolet spectropho-tometry was used for exploring the changes of content, solution appearance, and pH. Results: There were no evident changes in appearance and content, and pH was stable except cefuroxime sodium mixed with puerarin injection. Conclusions: Cefuroxime sodium individually mixed with etamsilate, Chuanhuning, p-aminomethylbenzoic acid in 0.9 % sodium chloride injection was feasible, but cefuroxime sodium mixed with puerarin in 0.9 % sodium chloride injection was unsuitalbe.