Functional activity of spleen and peripheral blood lymphocytes in stress-induced immunodepression |
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| Authors: | O. D. Yagmurov R. P. Ogurtsov |
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| Affiliation: | (1) Chair of Pathological Anatomy, I. P. Pavlov State Medical University, St. Petersburg;(2) Department of Immunology, Institute of Experimental Medicine, Russian Academy of Medical Sciences, St. Petersburg |
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| Abstract: | ![]()
Study of lymphoid organs and T and B cells in white rats shows that long-term stress causes progressive suppression of the immune response. Blockade of steroid hormone synthesis in the adrenal cortex prevents the development of immunodepression, implying a protective effect of such a blockade against stress-related secondary immunodeficiency. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 122, No. 7, pp. 64–68, July, 1996 |
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| Keywords: | stress lymphocytes immunodepression metapyrone |
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