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肿瘤患者血循环免疫复合物与尿N-乙酰-β-θ-氨基酸葡萄糖苷酶的相关性研究
引用本文:甘平,吴仲明.肿瘤患者血循环免疫复合物与尿N-乙酰-β-θ-氨基酸葡萄糖苷酶的相关性研究[J].贵州医药,1998(3).
作者姓名:甘平  吴仲明
作者单位:贵阳医学院附院肾内科
摘    要:观察恶性肿瘤患者血中循环免疫复合物(CIC)及尿中肾小管标志蛋白(N-乙酰-β-θ-氨基葡萄糖苷酶NAG)水平变化,探讨两者间相关关系及其意义。采用PEG沉淀比浊法检测血CIC水平;采用化学显色终点法定量检测尿NAG活力,共检测治疗前后恶性肿瘤患者49例。结果:肿瘤患者血CIC及尿NAG均较正常对照组明显增高,且治疗前较治疗后增高显著,血CIC与尿NAG水平变化是否相关(r=0.54P<0.01)。结果表明恶性肿瘤患者尿NAG活力显著增高与肿瘤相关抗原所致CIC水平有关。

关 键 词:恶性肿瘤  循环免疫复合物  肾小管标志蛋白

The relativity of serum cic and urinary nag in the patients with cancer
Can Pin,et al..The relativity of serum cic and urinary nag in the patients with cancer[J].Guizhou Medical Journal,1998(3).
Authors:Can Pin  
Abstract:The 49 patients with cancer were selected for this study in order to observe the changes of serum circulating immune ocmplex(ClC) theurinary N- Acetyl- Glucosaminidase(NAC ) in the patients with cancerand further to analyze theirs relativity. The results showed that serum ClC and urinary NAC were remarkably increased in these patients incomparison with the control. Senim ClC and Urinary NAC in patients before for treatment were higher than that in patients after treatment. It suggested that there is a positive reativity between serum ClCand urinary NAG in the patients with cancer.
Keywords:Cancer N-Acetyl-glucosaminidase Circulating Immune Complex
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