In vitro antibacterial activities of doripenem, imipenem, and meropenem against recent Streptococcus pneumoniae isolates |
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| Authors: | Baek Jin Yang Ko Kwan Soo Kang Cheol-In Song Jae-Hoon Peck Kyong Ran |
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| Affiliation: | aAsia Pacific Foundation for Infectious Diseases (APFID), Seoul 135-710, Korea;bDepartment of Molecular Cell Biology, Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, Suwon 440-746, Korea;cDivision of Infectious Diseases, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135-710, Korea |
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| Abstract: | ![]()
We investigated the in vitro activities of carbapenems against 347 Streptococcus pneumoniae isolates from Korea. While doripenem and imipenem resistance was displayed by only 1.2% and 3.2%, respectively, 21.3% of the isolates were resistant to meropenem. One isolate displaying very high carbapenem MICs and susceptibility only to vancomycin was also identified. |
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| Keywords: | Pneumococci Extreme drug resistance (XDR) Penicillin |
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