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Engineering Patient-Specific Valves Using Stem Cells Generated From Skin Biopsy Specimens
Authors:David L. Simpson  Brody Wehman  Yekaterina Galat  Sudhish Sharma  Rachana Mishra  Vasiliy Galat  Sunjay Kaushal
Affiliation:1. Division of Cardiac Surgery, University of Maryland Medical School, Baltimore, Maryland;2. Developmental Biology Program, iPS and Human Stem Cell Core Facility, Children''s Memorial Research Center, Northwestern University, Feinberg School of Medicine, Chicago, Illinois
Abstract:
Keywords:Ac-LDL, acetylated-low density lipoprotein   α-SMA, α-smooth muscle actin   BM-MSCs, bone marrow mesenchymal stem cells   CD, cluster of differentiation   DAPI, 4&prime  ,6-diamidino-2-phenylindole   DePV, decellularized pulmonary valve   DMEM, Dulbecco Modified Eagle's Medium   EC, endothelial cell   GAG, glycosaminoglycans   hESCs, human embryonic stem cells   iPSCs, induced pluripotent stem cells   iPSCs-ECs, induced pluripotent stem cells-endothelial cells   iPSCs-MSCs, induced pluripotent stem cells-mesenchymal stem cells   LDL, low-density lipoprotein   MSC, mesenchymal stem cell   PV, pulmonary valve   PVL, pulmonary valve leaflet   SRS, static-rotary-static   vWF, von Willebrand factor
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