基于五脏理论阐释干燥综合征的病机及诊治特点

干燥综合征在中医理论范畴称为"燥痹",临床症状复杂,患者多系先天禀赋不足、情志失调、饮食不节等,又遇外邪侵袭,导致五脏功能失调而相互影响,引起机体阴血津液损耗,输布障碍,不能外达四肢百骸及诸窍而致病。本文从五脏角度阐释燥痹病机及诊治特点,指出本病发病与心、肝、脾、肺、肾五脏均相关,其中尤以肾、脾、肝最为密切;病机以肾阴肾精亏虚为本,脾失健运、肝失调达为主,治以滋阴补肾、健脾益气、舒肝活血、清肺润燥、养心安神,同时配以养血生津、通络止痛、清热除湿等辨证治疗,其中养阴、益气、活血为治疗的关键。

Pathogenesis and diagnostic and therapeutic characteristics of Sjogren's syndrome based on TCM theory of five zang-organs

Sjogren's syndrome (SS),named as dry impediment in Chinese medicine,has complex clinical symptoms.It is mostly caused by constitutional insufficiency,emotional disorder and improper diet combining external pathogen attack,resulting in dysfunction and interaction of five zang-organs,overconsumption and distribution dysfunction of yin,blood and fluid-humor,and failing to arrive at all limbs,bones and orifices.The paper elucidates the pathogenesis and diagnostic and therapeutic characteristics of dry impediment,and indicates the disease is related to all five zang-organs (heart,liver,spleen,lung,kidney) while most closely related to kidney,spleen and liver.The pathogenesis of the disease is based on deficiency of kidney yin and essence,and mainly dominated by dysfunction of spleen in transportation and block of liver's free activity.The treatment of the disease,based on pattern differentiation,commonly use therapies of nourishing yin and tonifying kidney,fortifying spleen and tonifying qi,soothing liver and activating blood,clearing lung-heat and moistening dryness,and nourishing heart and tranquilizing mind,meanwhile matched with nourishing blood and engendering fluid,freeing collateral vessels and relieving pain,and clearing heat and eliminating dampness.Among these therapies,nourishing yin,tonifying qi and activating blood are keys in treatment.