颈动脉粥样硬化斑块MR成像的研究

目的 探讨多对比加权的MRI序列对颈动脉粥样硬化斑块检出并定性分析的价值。方法 采用采用1．5T磁共振仪、多对比加权序列3D—TOF、FSEPDWI、FSE—DIRT．WI、FSE—DIRPDWI、FSE—DIRT2WI对24例动脉粥样硬化的患者的35个颈动脉斑块进行MRI成像．分析斑块信号特征。结果 35个粥粥样斑块中18个斑块在所有序列上信号单一均匀；17个斑块在一个或多个序列上信号混杂，其中9个斑块含有脂质核心信号；9个斑块含钙化信号；1个表现为血管腔内血栓形成管腔闭塞。10个斑块可见厚纤维帽信号；23个表现为薄纤维帽信号特征；2个斑块表面不光滑。结论 采用多对比加权的MRI序列可以检出颈动脉粥样硬化斑块．并在一定程度上可对其进行成分分析。

The clinical study of carotid atherosclerotic plaque MRI

Objective To investigate the value of Multi contrast MRI in detection and qualitative analysis of human carotid atherosclerotic plaque. Methods Twenty-four patients with atherosclerosis underwent MR screening for carotid atherosclerotic plaques.The MR sequences included FSE-PDWI, 3D-TOF, FSE-DIRTIWI, FSE-DIRPDWI, FSEDIRT2WI. Signal and components of plaque were analyzed. Results 18 plaques demonstrated homogeneous signal intensity on each sequences. 17 plaques demonstrated heterogeneous signal intensity on at least one sequence. 9 plaques demonstrated the character of lipid core, 9 plaques of calcification and 1 of thrombosis in vessel cavity. 10 plaques presented the character of thick fibrous cap, while 23 plaques showed character of thin fibrous cap, The surface of 2 plaques were rough. Conclusion Multi contrast MR imaging sequences can be used for detection and qualitative analysis of the carotid atherosclerotic plaque to a certain extent.