| 低分子肝素治疗急性冠状动脉综合征患者的疗效观察 |
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| 引用本文： | 刘淑芳. 低分子肝素治疗急性冠状动脉综合征患者的疗效观察[J]. 医学研究杂志, 2005, 34(3): 36-37 |
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| 作者姓名： | 刘淑芳 |
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| 作者单位： | 辽宁大连医科大学附属第二医院心内科,116027 |
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| 摘 要： | 目的观察单用阿斯匹林和联合低分子肝素(法安明)治疗急性冠状动脉综合征(ACS)的临床疗效。方法将78例急性冠状动脉综合征,包括不稳定心绞痛和非 ST 段抬高的心肌梗死患者。随机分为对照组(阿斯匹林)及治疗组(阿斯匹林 法安明)疗程为一周,观察治疗前后:(1)临床疗效;(2)凝血指标的变化;(3)治疗后30天心绞痛再发率,急性心肌梗死(AMI)发生率。结果低分子肝素组总有效率91.43%,对照组总有效率58.3%(P<0.05)治疗组未发生不良反应。观察30天内心绞痛再发率及 AMI 发生率;治疗组12%和0,对照组39%和6.1%(P<0.05)。结论在常规阿斯匹林治疗基础上加用法安明,能更有效地控制心绞痛发作,减少心肌梗死发生率。
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| 关 键 词： | 阿司匹林 低分子肝素 急性冠脉综合征 |
| 修稿时间： | 2004-12-20 |
Low Molecular weight Heparin in the Treatment of Patient with Acute Coronary Syndromes. |
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| Liu Shufang. Low Molecular weight Heparin in the Treatment of Patient with Acute Coronary Syndromes.[J]. Journal of Medical Research, 2005, 34(3): 36-37 |
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| Authors: | Liu Shufang |
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| Affiliation: | Liu Shufang.Afficiatal Hospital Of Dalian Medical University.Dalian 116027 |
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| Abstract: | Objective To compare the effects of low-molecular-weight heparin(LMWH fragmin)and aspirin in patients with acute coronary syndromes.Methods A total of 78 patient with ACS was randomized into two groups receiving aspirin and aspirin plus LMWH(fragmin group)respectively for one week.Resuts The effect rate was 91.43% in the fragmin group and 58.3% in the aspirin group after one week(P< 0.05)no obvious adverse reaction was observed in the fragmin group.Conclusion Treatment with aspirin plus LMWH is more efficient,safe and convenient than aspirin alone during the acute stage of ACS. |
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| Keywords: | Aspirin Low-molecular-weight heparin Acute coronary syndromes |
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