| 吸入液中异丙托溴铵和苯扎氯铵的HPLC测定 |
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| 引用本文： | 汪洁. 吸入液中异丙托溴铵和苯扎氯铵的HPLC测定[J]. 中国医药工业杂志, 1996, 27(9): 413-415 |
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| 作者姓名： | 汪洁 |
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| 作者单位： | 上海市药品检验所 |
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| 摘 要： | 以阳离子交换色谱柱，用流动相０．０２ｍｏｌ／ＬＫＨ＿２ＰＯ＿４－乙腈（４５：５５），经高效液相色谱法测定爱喘乐吸入液中异丙托溴铵和苯扎氯铵的含量。方法灵敏、简便、重现性好，平均回收率分别为１０２．０％和９８．６％。
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| 关 键 词： | 异丙托溴铵；苯扎氯铵；吸入液；高效液相色谱法；测定 |
DETERMINATION OF IPRATROPIUM BROMIDE AND BENZALKONIUM CHLORIDE IN INHALATION BY HPLC |
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| WANG Jie. DETERMINATION OF IPRATROPIUM BROMIDE AND BENZALKONIUM CHLORIDE IN INHALATION BY HPLC[J]. , 1996, 27(9): 413-415 |
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| Authors: | WANG Jie |
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| Abstract: | The HPLC method was used for simultaneous determination of ipratropium bromide and benzalkonium chloride in Atrovent solution, using SCXcolumn. The mobile phase consisted of 0.02mol/L potassium dihydrogen phosphateacetonitrile(45:55),and UV detector at 210nm. The average recoveries of ipratropium bromide and benzalkonium chloride were 102.0% and 98.6% respectively. The method is accurate and simple. |
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| Keywords: | ipratropium bromide benzalkonium chloride inhalation HPLC determination |
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