Progress of Study on the Relationship Between Mediators of Inflammation and Apoptosis in Acute Pancreatitis |
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| Authors: | Xi-Ping Zhang Qian Lin Yi-Feng Zhou |
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| Affiliation: | (1) Department of General Surgery, Hangzhou First People’s Hospital, Hangzhou, 310006, Zhejiang Province, China;(2) Zhejiang College of Traditional Chinese Medical, Hangzhou, 310053, Zhejiang Province, China;(3) Department of Digest, Hangzhou First People’s Hospital, Hangzhou, 310006, Zhejiang Province, China |
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| Abstract: | ![]()
As an important pathological feature of acute pancreatitis, apoptosis may occur in multiple organs and relate directly to the progression of disease. It is mainly controlled by the apoptosis gene and also influenced by inflammatory mediators. We summarize here the roles of the main inflammatory mediators (e.g., NO, TNF-α, TGF-β1, IL-10, NF-κB) during the pathologic process of acute pancreatitis. We claim that this review is original, and we do not have any financial interest in a company or its competitor, and that all authors meet the criteria for authorship. |
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| Keywords: | Acute pancreatitis Severe acute pancreatitis Inflammatory mediators Apoptosis Nitric oxide Cytokine Nuclear factor-κ B |
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