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胃癌与性激素及其受体的研究新进展
引用本文:郑晓,蒋敬庭,吴昌平. 胃癌与性激素及其受体的研究新进展[J]. 医学综述, 2009, 15(3): 342-345
作者姓名:郑晓  蒋敬庭  吴昌平
作者单位:苏州大学第三附属医院肿瘤生物诊疗中心,江苏常州,213003
摘    要:胃癌的发生及其生物学行为与性激素有关。血清性激素水平的测定对探讨胃癌发病有一定的指导作用。性激素受体在胃癌中的表达与胃癌的发生发展有着密切的联系。性激素受体作为一种肿瘤生物学标记,对胃癌的转移和预后有一定的意义。性激素受体相关药物较其他抗癌药物不良反应小、特异性强、疗效好,有着广阔的临床应用前景。

关 键 词:胃癌  血清性激素水平  性激素受体  转移和预后  内分泌治疗

Advancement on Gonadal Hormone and Receptor in Gastric Cancer
ZHENG Xiao,JIANG Jing-ting,WU Chang-ping. Advancement on Gonadal Hormone and Receptor in Gastric Cancer[J]. Medical Recapitulate, 2009, 15(3): 342-345
Authors:ZHENG Xiao  JIANG Jing-ting  WU Chang-ping
Affiliation:. ( Center for Biological Diagnosis and Therapy, the Third Affiliated Hospital of Suzhou University, Changzhou 213003, China )
Abstract:The incidence and biological behavior of gastric cancer is related to sex hormone. Determinations of serum levels of sex hormones have a certain guiding role on the incidence of gastric cancer. The expressions of sex hormone receptors in gastric cancer are closely linked to the occurrence and development of gastric cancer. Sex hormone receptors are regarded as a kind of tumor biological markers, which have great significance in the metastasis and prognosis of gastric cancer. Compared to other anti-cancer drugs, sex hormone receptor-related drugs have minor adverse effects, a high specificity and a good curative effect, which have a broad prospect for clinical application.
Keywords:Gastric cancer  Serum level of sex hormone  Sex hormone receptor  Metastasis and prognosis  Endocrine therapy
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