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| 天灸对哮喘模型大鼠血清白细胞介素-4、白细胞介素-6及IgE的影响 | |
| 引用本文： | 朱书秀,周丽莎,涂乾,朱青艳,王芳. 天灸对哮喘模型大鼠血清白细胞介素-4、白细胞介素-6及IgE的影响[J]. 时珍国医国药, 2007, 18(7): 1582-1583 |
| 作者姓名： | 朱书秀 周丽莎 涂乾 朱青艳 王芳 |
| 作者单位： | 江汉大学医学与生命科学院,湖北,武汉,430056 |
| 基金项目： | 武汉市科技局资助项目(No.20025007170) |
| 摘 要： | 目的研究血清IL-4,IL-6及IgE在哮喘发病中的作用及天灸对它们的影响。方法40只雄性大鼠随机分为正常组、模型组、天灸组及电针组。用卵蛋白(OVA)致敏来制备哮喘模型大鼠。ELISA法检测血清IL-4,IL-6及IgE。结果模型组血清IL-4,IL-6及IgE高于正常组(P<0.01),经治疗后均有所降低,且天灸组最显著。结论支气管哮喘的发病与血清IL-4,IL-6及IgE的异常有关,天灸对其具有调节作用。 |
| 关 键 词： | 天灸 白细胞介素-4 白细胞介素-6 IgE |
| 文章编号： | 1008-0805（2007）07-1582-02 |
| 收稿时间： | 2006-12-28 |
| 修稿时间： | 2006-12-282007-03-12 |
Effect of Tianjiu on the Serum IL-4, IL-6 and IgE in Asthmatic Rats |
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| ZHU Shu-xiu,ZHOU Li-sha,TU Qian,ZHU Qing-yan,WANG Fang. Effect of Tianjiu on the Serum IL-4, IL-6 and IgE in Asthmatic Rats[J]. Lishizhen Medicine and Materia Medica Research, 2007, 18(7): 1582-1583 | |
| Authors: | ZHU Shu-xiu ZHOU Li-sha TU Qian ZHU Qing-yan WANG Fang |
| Affiliation: | Medicine and Life Sciences Institute , Jianghan University, Wuhan 430056, China |
| Abstract: | Objective To investigate the function of serum IL-4,IL-6 and IgE in asthma occurance,observe the effect of Tianjiu on them.Methods 40 male rats were divided randomly into the normal group,model group,Tianjiu-treated group and the electric needle-treated group.The asthma model of big rats were sensitized by ovalbumen(OVA)and incited with inhaling fog.The serum IL-4,IL-6 and IgE were examined by ELISA method.Results The serum IL-4,IL-6 and IgE of the model group was obviously higher than that of the normal group(P<0.01),and their contents were reduced by treatment,especially Tianjiu-treated group.Conclusion Occurrance of asthma is related to abnormality of serum IL-4,IL-6 and IgE.Tianjiu can adjust them. |
| Keywords: | Tianjiu IL-4 IL-6 IgE |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |