Investigation of three new mouse mammary tumor cell lines as models for transforming growth factor (TGF)-β and Neu pathway signaling studies: identification of a novel model for TGF-β-induced epithelial-to-mesenchymal transition |
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| Authors: | Anne EG Lenferink Joanne Magoon Christiane Cantin Maureen D O'Connor-McCourt |
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| Affiliation: | (1) Receptor, Signaling and Proteomics Group, National Research Council, Biotechnology Research Institute, Montr?al, Queb?c, Canada |
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| Abstract: | Introduction This report describes the isolation and characterization of three new murine mammary epithelial cell lines derived from mammary tumors from MMTV (mouse mammary tumor virus)/activated Neu + TβRII-AS (transforming growth factor [TGF]-β type II receptor antisense RNA) bigenic mice (BRI-JM01 and BRI-JM05 cell lines) and MMTV/activated Neu transgenic mice (BRI-JM04 cell line). |
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