贲门失弛缓症内镜下球囊扩张治疗及复发的预测因素

目的 :观察球囊扩张治疗贲门失弛缓症的疗效及复发率 ,探讨贲门失弛缓症球囊扩张治疗后复发的预测因素。方法 :应用球囊扩张治疗并随访半年以上 ,比较复发组与非复发组在性别、年龄、病程、食管最大径、球囊扩张直径、球囊扩张类型及扩张时间等方面的差异 ,并进行多因素Logistic回归分析。结果 :球囊扩张治疗贲门失弛缓症有效率为 10 0 % ,复发率为 2 3.3% ,复发组与非复发组在年龄及病程两方面存在差异 ,病程的回归系数为 - 1.35 8(P <0 .0 5 )。结论 :球囊扩张术是治疗贲门失弛缓症有效的方法 ,但存在一定的复发率 ,病程是贲门失弛缓症球囊扩张治疗后复发的唯一预测因素。

THE DILATATION TREATMENT IN PATIENTS WITH ACHALASIA AND THE PREDICTIVE FACTOR OF RECURRENCE

Objective:To observe the efficacy of dilatation treatment in patients with achalasia and the recurrence rate after the dilatation treatment. To investigate the predictive factor of recurrence after the dilatation treatment in patients with achalasia.Methods:Forty-three cases with achalasia were treated with dilatation of balloon under endoscopy and were followed up for more than 6 months. The recurrence group was compared with the non-recurrence group in sex, age, course of disease, the maximun diameter of esophageal, the dilatation diameter of balloon, the dilatation type of balloon and the duration of dilatation.Results:The effective rate of the dilatation treatment in achalasia was 100%. The recurrence rate was 23.3%. There were significant differences in age and course of disease between the two groups ( P <0.05).The regression coefficient of the course of disease was -1.358 ( P < 0.05 ).Conclusion:The dilatation treatment under endoscopy is an effective therapy in achalasia, but there are chances of recurrence. The course of disease is a unique factor in predicting recurrence after the dilatation treatment in patients with achalasia.