阻塞性睡眠呼吸暂停综合征患者睡眠时咽腔观察

目的 分析阻塞性睡眠呼吸暂停综合征（ｏｂｓｔｒｕｃｔｉｖｅ ｓｌｅｅｐ ａｐｎｅａ ｓｙｎｄｒｏｍｅ，ＯＳＡＳ），患者睡眠时咽腔阻塞特点及解剖原因，并与清醒时Ｍｕｌｌｅｒｘ检查比较。方法 纤维喉镜检查４３例睡眠ＯＳＡＳ患者咽腔。结果 ①所有睡眠患者都有腭咽部阻塞，７９％病例合并口咽和／或下咽部阻塞。②咽阻塞涉及软腭或悬雍垂后坠、咽壁内陷、扁桃体或咽腭弓肥大、咽皱襞和咽侧索冗赘、舌根肥厚及后坠等诸多

Pharyngoscopic observation during sleep in patients with obstructive sleep apnea syndrome]

OBJECTIVE: To analyse collapse sites of pharynx and their anatomical causes during sleep in patients with obstructive sleep apnea syndrome(OSAS), and compared with the results of Muller's maneuver. METHODS: The pharynges in 43 sleeping patients with OSAS were examined endoscopically. The area changes at each segment(velo-, oro- and hypopharynges) were calculated during the episodes of apnea. A site having greater than 75% narrowing of airway lumen was defined as a narrowing or obstructive site. RESULTS: 1. All patients had obstruction at velopharynx during asleep. Airway collapses at multiple sites in 79% of cases(28% at velo- and oropharynx; 21% at velo- and hypopharynges; and 30% at velo-, oro- and hypopharynges). 2. At each segment the anatomical factors causing obstruction were variable among patients. The common abnormalities were posterior displacement of soft palate or uvula, enlarged tonsil, thicken or posterior displacement of tongue base, collapse of pharyngeal wall, redundant mucosa or lateral bands of pharynx etc. 3. The positivity of pharyngeal obstruction was higher in this study as compared with of Muller's maneuver the latter was taken place while the patient was awaken. Comparison of the positive rate of the narrowing sites determined between sleep observation and Muller's maneuver in same patients: at velopharynx(100% vs 91%), at oropharynx (58% vs 42%) and at hyperpharynx (51% vs 28%). CONCLUSION: Multiple obstructions in the pharynx are common. Examination of the pharynx during asleep may be more accurate then while the patient was awaken.