| 肿瘤放射增敏药物的研究进展 |
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| 引用本文： | 章鹤,宋建元,曹建平.肿瘤放射增敏药物的研究进展[J].国际放射医学核医学杂志,2014,38(6):408-411. |
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| 作者姓名： | 章鹤 宋建元 曹建平 |
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| 作者单位： | 江苏省放射医学与防护重点实验室,苏州大学医学部放射医学与防护学院,215123 |
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| 基金项目： | 国家自然科学基金，江苏省高校重大科研项目 |
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| 摘 要： | 放射治疗是临床肿瘤治疗的重要手段之一.肿瘤细胞的放射敏感性是影响肿瘤放疗疗效的关键因素.放射增敏药物能够增强机体的放射敏感性,通过提高肿瘤细胞的放射敏感性达到降低照射剂量、提高放疗疗效、降低正常组织损伤的目的.现有的放射增敏药物主要分为细胞毒类药物、靶向药物以及中药制剂3大类.该文将对肿瘤放射增敏药物的作用机制、现状及相关研究进展进行综述.
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| 关 键 词： | 肿瘤 放射疗法 放射增敏药物 |
The research progression of cancer radio-sensitization drugs |
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| Zhang He,Song Jianyuan,Cao Jianping.The research progression of cancer radio-sensitization drugs[J].International Journal of Radiation Medicine and Nuclear Medicine,2014,38(6):408-411. |
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| Authors: | Zhang He Song Jianyuan Cao Jianping |
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| Institution: | (Jiangsu Provincial Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Medical College of Soochow University, Suzhou 215123, China) |
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| Abstract: | Radiation therapy occupies an irreplaceable position for cancer therapy.The sensibility of the tumor is a fundamental factor that influences the treatment effectiveness.The drug of radiosensitization can reinforce the radiosensitivity by raising the sensitivity of the tumors in order to decrease the expose dose and the lesion of normal tissue.At present there are cytotoxic drug,targeted drug and Chinese drugs pharmaceutics.This article reviews the mechanism of action,status quo and research progression of the radiosensitization drugs. |
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| Keywords: | Neoplasms Radiation therapy Radiosensitization |
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