| The Inhibitory Effect of Radix Salviae Miltiorrhizae on Hypoxic Structural Remodeling of Intra－acinarPulmonary Arteries |
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| 引用本文： | 席思川,车东媛,张婉蓉. The Inhibitory Effect of Radix Salviae Miltiorrhizae on Hypoxic Structural Remodeling of Intra－acinarPulmonary Arteries[J]. 华中科技大学学报(医学英德文版), 1994, 14(3): 148-152. DOI: 10.1007/BF02886795 |
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| 作者姓名： | 席思川 车东媛 张婉蓉 |
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| 作者单位： | Department of Pathology，Tongji Medical University，Wuhan Present address: Department of Pathology，Cardiovascular institute and Fuwai Hospital，Chinese Academy of Medical Sciences，Beijing |
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| 摘 要： | (席思川)(车东媛)(张婉蓉)ＴｈｅＩｎｈｉｂｉｔｏｒｙＥｆｆｅｃｔｏｆＲａｄｉｘＳａｌｖｉａｅＭｉｌｔｉｏｒｒｈｉｚａｅｏｎＨｙｐｏｘｉｃＳｔｒｕｃｔｕｒａｌＲｅｍｏｄｅｌｉｎｇｏｆＩｎｔｒａ－ａｃｉｎａｒＰｕｌｍｏｎａｒｙＡｒｔｅｒｉｅｓ￥ＸＩＳｉ－ｃ...
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| 收稿时间： | 1993-10-07 |
The inhibitory effect of radix salviae miltiorrhizae on hypoxic structural remodeling of intra-acinar pulmonary arteries |
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| Xi Si-chuan,Che Dong-yuan,Zhang Wan-rong. The inhibitory effect of radix salviae miltiorrhizae on hypoxic structural remodeling of intra-acinar pulmonary arteries[J]. Journal of Huazhong University of Science and Technology. Medical sciences, 1994, 14(3): 148-152. DOI: 10.1007/BF02886795 |
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| Authors: | Xi Si-chuan Che Dong-yuan Zhang Wan-rong |
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| Affiliation: | (1) Department of Pathology, Tongji Medical University, Wuhan;(2) Present address: Department of Pathology, Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences, Beijing |
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| Abstract: | The inhibitory effect of Radix Salviae Miltiorrhizae (RSM) on hypoxic structural remodeling of intra-acinar pulmonary arteries (IAPA) was observed by light and electron microscopy and morphometry. It was found that RSM can not only dilate IAPA and relieve the hypoxic injuries to endothelia cells,but also inhibit the active muscularization of IAPA in the hypoxic animals, suggesting that RSM plays a very important role in inhibiting structural remodeling of IAPA and pulmonary hypertension. |
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| Keywords: | radix salviae miltiorrhizae hypoxia pulmonary hypertension endothelial cell |
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