Mechanisms of drug interactions II: pharmacokinetics and pharmacodynamics

This article complements that of Corrie and Hardman (2011) as it dwells specifically on drug interactions in pharmacokinetics. It emphasizes how pharmacokinetics is influenced by drug–drug and drug–disease interactions. Common examples, in anaesthesia and intensive care settings, are illustrated. It then concludes in reaffirming pharmacodynamic interactions in the article cited.