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| 银杏叶黄酮对小鼠和大鼠肝脏脂质过氧化的影响 | |
| 引用本文： | 唐祖年,韦玉先,梁荣感,马孟斌. 银杏叶黄酮对小鼠和大鼠肝脏脂质过氧化的影响[J]. 华夏医学, 1995, 0(3) |
| 作者姓名： | 唐祖年 韦玉先 梁荣感 马孟斌 |
| 作者单位： | 桂林医学院药理教研室 |
| 摘 要： | 本文采用硫代巴比妥酸反应法，观察了银杏叶黄酮对小鼠和大鼠正常肝匀浆及四氯化碳（ｃｃｌ４）引起的脂质过氧化作用的影响，并观察了对小鼠血清ＳＧＰＴ的影响。结果表明，银杏叶黄酮对体外小鼠和大鼠肝匀浆及ｃｃｌ４引起的脂质过氧化均有显著降低。而对体内小鼠的脂质过氧化及ｃｃｌ４诱导的ＳＧＰＴ升高无明显影响。 |
| 关 键 词： | 银杏叶黄酮；脂质过氧化，硫代巴比妥酸反应；肝匀浆。 |
Effect of Ginkgoglycosides on Lipid Peroxidation in the Liver of Mice and Rats |
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| /Tang Zhunian,Wei Yuxian,Liang Ronggan,et al. Effect of Ginkgoglycosides on Lipid Peroxidation in the Liver of Mice and Rats[J]. Acta Medicinae Sinica, 1995, 0(3) | |
| Authors: | /Tang Zhunian Wei Yuxian Liang Ronggan et al |
| Abstract: | This study was performed to examine both in vitro and in vivo the effect of ginkgoglycosides extracted from leaves of ginkgo biloba L. on lipid peroxidation in liver homogenates.The thiobarbituric acid reaction was used to measure lipid peroxidation in both normal and CCl4-induced lipid peroxidation in liver homogenates of mice and rats. Meanwhile,serum pyruvate transaminase(SGPT)was also determined in the mice.The results showed in vitro that ginkgoglycosides extracted from leaves of kingo biblo L. significantly reduced CCl4-induced lipid peroxidation in mouse and rat liver homogenates,(p<0. 001).No obvious effect,however,was observed in vivo on lipid peroxidation in liver homogenates or on SGPT in the mice. |
| Keywords: | ginkgoglycoside lipid peroxidation thiobarbituric acid reaction liver homogenates |
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