腹腔镜宫颈癌根治术治疗早期宫颈癌的安全性和有效性分析

目的 探讨腹腔镜宫颈癌根治术与开腹宫颈癌根治术治疗早期宫颈癌的临床疗效.方法 回顾性分析104例早期宫颈癌患者的临床资料,根据治疗方式的不同将患者分为观察组(n=52)和对照组(n=52),观察组患者行腹腔镜下宫颈癌根治术,对照组患者行开腹宫颈癌根治术.比较两组患者的术中出血量、手术时间、术后住院时间及并发症发生率;随访8~60个月,比较两组患者的局部复发率和累积生存率.结果 观察组患者的术中出血量明显少于对照组,手术时间和术后住院时间均明显短于对照组,差异均有统计学意义(P﹤0.01).两组患者输尿管损伤、膀胱损伤、肠道损伤、血管损伤、尿潴留、伤口愈合不良、盆腔感染并发症发生率比较,差异均无统计学意义(P﹥0.05).两组患者的局部复发率和5年累积生存率比较,差异均无统计学意义(P﹥0.05).结论 采用腹腔镜宫颈癌根治术可缩短早期宫颈癌患者的手术时间和术后住院时间,减少术中出血量,减轻机体创伤,且不增加局部复发率,未降低远期生存率,是一种安全有效的治疗方式.

Safety and efficacy analysis of laparoscopic radical hysterectomy in the treatment of early cervical cancer

Objective To observe the clinical effect of laparoscopic radical hysterectomy and laparotomy in the treat-ment of early cervical cancer.Method 104 cases of early cervical cancer patients were retrospectively analyzed,these patients were assigned as study group(n=52)or control group(n=52)according to the treatment administered,the study group received laparoscopic radical hysterectomy,while the control group was treated with laparotomy for cervical can-cer. The intraoperative blood loss, operative time, hospital stay, and the incidence of complications were compared be-tween the two groups;all patients were followed up for 8-60 months,the local recurrence rate and cumulative survival rate were compared. Result The intraoperative blood loss, operative time and postoperative hospital stay in the study group were significantly less or lower than that in the control group,with significant difference observed(P<0.01).As for the local recurrence rate, the incidence of ureteral injury, bladder injury, intestinal injury, vascular injury, urinary reten-tion,poor would healing,and pelvic infections were similar between the two groups,the differences were not statistically significant(P>0.05).The local recurrence rate and 5-year cumulative survival rate showed no significant difference be-tween the two groups(P>0.05).Conclusion Laparoscopic radical hysterectomy can shorten the operative time and hos-pital stay,and may reduce intraoperative blood loss,minimize the wound,and would neither increase the local recurrence rate nor reduce the long-term survival rate,and it is a safe and effective treatment.