妊娠合并卵巢肿瘤的临床诊断和妊娠结局分析

目的:探讨妊娠合并卵巢肿瘤的临床诊断和妊娠结局，总结预防感染措施。方法:随机选取2011年2月-2013年4月75例妊娠合并卵巢肿瘤患者为研究对象，作为观察组，同时期的75例妊娠合并瘤样病变患者为对照组。从临床表现、辅助检查上比较妊娠合并卵巢肿瘤患者临床特征，并分析其妊娠结局，观察采取预防感染措施后感染发生情况。结果:妊娠合并卵巢肿瘤通常无明显的临床症状，有症状则以恶心呕吐、腹痛等为主。和瘤样病变比较，其肿瘤直径增大明显，肿瘤血流阻力指数下降，孕期肿块均较瘤样病变明显。观察组CA125增高46例，平均值为（31.53±14.73）U/ml，对照组CA125增高41例，平均值为（29.27±12.23）U/ml，两组比较无明显差异性（P>0.05）。两组患者CA199、CEA、AFP检测结果比较差异无统计学意义，均在正常范围内。妊娠合并卵巢肿瘤的妊娠结局以足月产为主，占全部的74.67%，早产和流产占全部的25.33%。在不同时间段有不同的妊娠结局，＜12周以流产为主，12-28周以早产和流产较多，>28周-足月则以足月产为主。感染发生率为4%。结论:妊娠合并卵巢肿瘤通常无临床症状，超声和实验室检查有助于鉴别诊断，早期干预对妊娠结局至关重要。

Pregnancy outcomes of pregnant women with ovarian cancer

Objective:To investigate the clinical pregnancy diagnosis of ovarian cancer and pregnancy outcomes，infection prevention measures.Methods:Randomly selected 75 pregnant women with ovarian cancer as the observation group，75 cases with tumor-like lesions with pregnancy in the same period as the control group.Clinical manifestations，laboratory exam were observed and to analyze the outcome of pregnancy.Results:Pregnancy ovarian tumors usually had no obvious clinical symptoms.In observation group 46 cases CA125 increased，with an average of （31.53±14.73)U/ml，in the control group CA125 increased in 41 cases with an average of （29.27±12.23)U/ml （P>0.05).There were no differences in CA199，CEA，AFP.Ovarian tumors in pregnancy to full-term pregnancy outcome，accounting for 74.67% of all rather premature birth and miscarriage of 25.33% of the total.And in different time periods with different pregnancy outcomes，<12 weeks to abortion based，and 12-28 weeks premature birth and abortion was more.>28 weeks-term places full-term oriented.Conclusion:Pregnancy ovarian tumors are usually no clinical symptoms，ultrasound and laboratory tests can help the differential diagnosis，and early intervention is crucial to pregnancy outcome.