急性氯氰菊酯中毒合并急性酒精中毒的临床探讨

目的探讨急性氯氰菊酯中毒合并急性酒精中毒时，血浆酒精浓度及氯氰菊酯浓度相关性及此类患者的预后。方法对60例急性氯氰菊酯中毒患者，根据中毒前是否饮酒分为混合中毒组与单纯中毒组，所有患者行血浆氯氰菊酯浓度检测，对混合中毒组患者行血浆酒精浓度检测；对两组患者的一般资料（性别、年龄、氯氰菊酯浓度）及死亡率进行统计学处理，并对酒精浓度与氯氰菊酯浓度相关性进行分析。结果两组患者存在性别差异，混合中毒组男性明显高于女性（P〈O．05）；混合中毒组患者血液中氯氰菊酯含量、病死率明显升高（P〈O．05）；混合中毒组患者血浆酒精浓度与血液中氯氰菊酯浓度呈正相关，饮酒量越多，氯氰菊酯中毒程度越重。结论急性氯氰菊酯合并急性酒精中毒时，血液中氯氰菊酯浓度明显升高，病死率增加。

Clinical study of acute cypermethrin poisoning affiliated with acute alcohol intoxication

Objective To determine the effects of plasma concentration of alcohol on blood cypermethrin concentration and the prognosis of the patients when acute cypermethrin poisoning affiliated with acute alcohol intoxication. Methods 60 cypermethrin poisoning cases were divided into mixed cypermethrin group and cypermethrin group, blood samples were taken on admission from patients, the cypermethrin concentration were detected, blood alcohol concentration also detected in mixed group. Sex, age, cypermethrin concentration, mortality rate were analysised, meanwhile, speaman correlation were used to investigate whether associations between alcohol and cypermethrin. Results Compared with patients with no alcohol in their blood, patients with detectable alcohol were more likely to be male, the cypermethrin concentration and death rate were more higher than control group （P〈0.05）. There was a positive correlation between alcohol and cypermethrin levels. Conclusion Acute cypermethrin poisoning affiliated with acute alcohol intoxication is associated with higher blood concentrations of cypermethrin and increased risk of death.