| Abstract: | ![]()
Removal of the thymus strengthened and prolonged tolerance to sheep's red blood cells obtained with the aid of cyclophosphamide if thymectomy was performed on the mice before or after the induction of tolerance. Thymectomy had its greatest effect if performed 24 h before the induction of tolerance. The results confirm the view that this form of tolerance is due to a deficiency of a definite clone of T helpers.Laboratory of Immunologic Tolerance, N. F. Gamaleya Institute of Epidemiology and Microbiology, Academy of Medical Sciences of the USSR, Moscow. (Presented by Academician of the Academy of Medical Sciences of the USSR P. A. Vershilova.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 86, No. 12, pp. 707–709, December, 1978. |
