Risk factor analysis for metaplastic gastritis in Koreans |
| |
Authors: | Choi Soonami Lim Yun Jeong Park Sue Kyung |
| |
Affiliation: | 1. Center for Health Promotion, Samsung Medical Center, Seoul, Korea 2. Department of Internal Medicine, Dongguk University International Hospital, Dongguk University College of Medicine, Goyang, Korea 3. Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea |
| |
Abstract: | AIM: To conduct a retrospective study to determine the risk factors for development of metaplastic gastritis in Korean population. METHODS: The database of 113449 subjects who underwent a gastroscopy for the purpose of a regular check-up at center for health promotion, Samsung medical center during 5 years was collected and retrospectively analyzed. Among them, 5847 subjects who had endoscopically diagnosed as a metaplastic gastritis or 10076 normal as well as answered to questionnaire were included for present study. The subjects were divided into 2 groups; Group I, normal and Group II, metaplastic gastritis. Age, gender, Helicobacter pylori (H pylori) seropositivity, body mass index (BMI), family history of cancer, smoking, alcohol consumption, total daily calories, folate and salt intake and dietary habit (out-eating, overeating, irregular eating) were retrieved from questionnaire or electronic medical record and compared between group I and group II. RESULTS: The prevalence of group II was 11% (13578/113449) increasing its prevalence with age (P = 0.000). But, there was no significant association between 2 groups in BMI, family history of cancer, alcohol consumption, total daily calories, folate and salt intake and dietary habit (out-eating, overeating, irregular eating). Old age (P=0.000), male gender (P = 0.000), H pylori seropositivity (P = 0.010) and current smoker (P = 0.000) were significantly more common in group II at multiple logistic regression model. CONCLUSION: Our data suggested that old age, male gender, H pylori seropositivity and smoking were risk factors for metaplastic gastritis, precancerous lesion of gastric cancer. |
| |
Keywords: | Intestinal metaplasia Risk factors |
本文献已被 CNKI 维普 万方数据 PubMed 等数据库收录! |
|