| 非霍奇金淋巴瘤染色体异常与组织学及免疫学表型相关性的探讨 |
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| 引用本文： | 李晓莉,韩传贵,李丽.非霍奇金淋巴瘤染色体异常与组织学及免疫学表型相关性的探讨[J].白血病．淋巴瘤,1996(1). |
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| 作者姓名： | 李晓莉 韩传贵 李丽 |
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| 作者单位： | Li Xiaoli，Han Chuangui，Li Li. The Third Affiliated Hospital of Haerbin Medical Universitg，Haerbin 150040 ] |
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| 摘 要： | 应用短期培养法对２４例非霍奇金淋巴瘤（ＮＨＬ）进行核型分析，同时对该组病例进行免疫学分型和组织学分类。２４例ＮＨＬ除１例无分裂相外，均出现克隆性染色体异常，数目异常主要是亚二倍体，超二倍体、四倍体；数目的丢失、获得是非随机的，６ｑ－最多见，主要见于ＳＬ、ＤＬ、ＩＢＬ；１４ｑ＋多见，主要见于ＳＬ、ＤＬ及ＬＢＬ，同时与供体不同有关。Ｔ细胞淋巴瘤多见１４、７、６、１２、１９号染色体异常，Ｂ细胞淋巴瘤可见ｔ（１４，１８）（ｑ３２，ｑ２１）
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| 关 键 词： | 非霍奇金淋巴瘤 染色体 T淋巴瘤 B淋巴瘤 |
DISCUSSION ON CHROMOSOMAL ABNORMALITIES IN NON HODGKIN'S LYMPHOMA WITH THE HISTOLOGIC AND IMMUNOPHENOTYPIC CORRELATION |
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| Li Xiaoli,Han Chuangui,Li Li.DISCUSSION ON CHROMOSOMAL ABNORMALITIES IN NON HODGKIN''''S LYMPHOMA WITH THE HISTOLOGIC AND IMMUNOPHENOTYPIC CORRELATION[J].Journal of Leukemia & Lymphoma,1996(1). |
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| Authors: | Li Xiaoli Han Chuangui Li Li |
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| Institution: | Li Xiaoli,Han Chuangui,Li Li. The Third Affiliated Hospital of Haerbin Medical Universitg,Haerbin 150040 ] |
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| Abstract: | We studied the involved lymph nodes in 24 patients with Non Hodgkin's lymphomas. The results were that clone chromosome abnormalities appeared on 23 cases. In the 24 cases, 19 T lymphomas, 5 B lymphomas, eight of the nineteen T lymphomas were SL. The gain or loss of chromosome was not randomized. Chromosome abnormalities were more in 6q - and 14q . Our results indicated that patients of T lymphomas are more. Analysis under microscope for T, B types were not exact, and need studing further by immunohistology. |
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| Keywords: | Non Hodgkin's lymphoma Chromosome T lymphoma B lymphoma |
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