New antimycobacterial triterpenoids from Rhus taitensis |
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Authors: | Jadulco Raquel C Koch Michael Van Wagoner Ryan M Pond Christopher Gideon Osia G Matainaho Teatulohi Piskaut Pius Barrows Louis R |
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Affiliation: | Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah, USA. |
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Abstract: | Two new triterpenoids were isolated from the leaves and twigs of Rhus taitensis. Their structures were elucidated by 1D and 2D NMR spectroscopic studies as 1,10,24,25,30-pentahydroxysqualene and dammar-20(22),24-diene-3 β,26,27-triol. Both compounds exhibited moderate antimycobacterial activities with an MIC of 45 μg/mL. |
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