| 塞克硝唑片治疗牙周炎的临床研究 |
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| 引用本文： | 陈穗,;张汉东,;曾久荷,;龚培力. 塞克硝唑片治疗牙周炎的临床研究[J]. 中国药房, 2009, 0(2): 131-133 |
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| 作者姓名： | 陈穗, 张汉东, 曾久荷, 龚培力 |
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| 作者单位： | [1]华中科技大学同济医学院附属协和医院口腔科,武汉市430022; [2]华中科技大学同济医学院药学系,武汉市430000 |
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| 摘 要： | 目的:评价塞克硝唑片治疗牙周炎的疗效和安全性。方法:61例牙周炎患者,采用多中心、随机、双盲、平行对照试验设计,比较试验组(塞克硝唑片,n=33)与对照组(替硝唑片,n=28)的临床疗效和安全性。结果:试验组与对照组治疗牙周炎的有效率分别为15.2%、14.3%(P>0.05);2组安全性皆很好,无显著性差异(P>0.05)。结论:塞克硝唑片治疗牙周炎疗效与替硝唑相当,安全。
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| 关 键 词： | 塞克硝唑 牙周炎 厌氧菌 |
Clinical Study on Secnidazole in Patients with Periodontitis |
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| Affiliation: | CHEN Sui, ZHANG Han-dong, ZENG Jiu-he, GONG Pei-li(1.Dept. of Stomatology, Union Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China;2.College of Huazhong University of Science and Technology, Wuhan 430000,China) |
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| Abstract: | OBJECTIVE： To evaluate the efficacy and safety of Secnidazole in patients with periodontitis. METHODS： This study was a multicenter, randomized, double- blind, parallel -controlled trial in which 33 periodontitis cases were treated by Secnidazole tablets （trial group）, and 28 by Tinidazole tablets （control group） . RESULTS： There were significant differences between the trial group and the control group in effective rate （15.2% versus 14.3% ） （P 〉0.05） . Nor were there significant differences between the two groups in safety. CONCLUSION： The therapeutic effect and safety of Secnidazole is similar to Tinidazole in patients with periodontitis. |
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| Keywords: | Secnidazole Periodontitis Anaerobic |
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