2种用药方案治疗心绞痛的最小成本分析

目的:评价2种用药方案治疗心绞痛的疗效和经济学效果。方法:将104例心绞痛住院患者按入院先后顺序分为2组,除均予以相同基础治疗外,分别给予单硝酸异山梨酯氯化钠注射液(A组,n=56)、硝酸异山梨酯注射液(B组,n=48)治疗10d,采用最小成本分析法进行评价。结果:A组与B组总有效率分别为94.64%、95.83%(P>0.05),不良反应发生率分别为7.14%、8.33%(P>0.05),总成本分别为1382.80、1573.80元。结论:A组方案治疗心绞痛较经济。

Cost - Minimization Analysis of Two Therapeutic Schemes for Angina Pectoris

OBJECTIVE： To evaluate the therapeutic efficacy and pharmacoeconomic results of Isosorbide Mononitrate Sodium Chloride Injection versus Isosorbide Dinitrate Injection for the treatment of angina pectoris. METHODS： A total of 104 inpatients with angina peetoris were divided into 2 groups according to the order in which they were admitted to hospital： 56 cases in Group A were assigned to receive Isosorbide Mononitrate and Sodium Chloride Injection and 48 in Group B to receive Isosorbide Dinitrate Injection for 10 days. The cost- minimization analysis was performed on the two groups. RESULTS： The total effective rate was 94.64% in Group A and 95.83% in Group B （P 〉 0.05） . Theincidenee rates of adverse reaction were 7.14% and 8.33% respectively （P 〉 0.05） . The total costs were 1 382.80 yuan and 1 573.80 yuan respectively. CONCLUSION： Group A was optimal for angina pectoris.