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扩张型心肌病患者心脏再同步化治疗的疗效观察
引用本文:徐茂椿,邱建平,张瑜,朱华,刘淼,孙敏敏.扩张型心肌病患者心脏再同步化治疗的疗效观察[J].临床心血管病杂志,2010,26(2).
作者姓名:徐茂椿  邱建平  张瑜  朱华  刘淼  孙敏敏
作者单位:1. 上海浦东新区公利医院心内科,上海,200135
2. 上海浦东新区公利医院心脏超声室
3. 上海市中山医院心脏超声室
摘    要:目的:观察在组织多普勒指导下对药物难治性扩张型心肌病(DCM)充血性心力衰竭的心脏再同步化治疗(CRT)的疗效。方法:选择18例经药物治疗后无效的DCM充血性心力衰竭患者行CRT。术前行二维超声心动图和组织多普勒检查,术后1周在组织多普勒指导下行房室和室间延迟优化。术后1个月、3个月、6个月及1年随访患者的临床症状,并比较各项参数的变化。结果:CRT后①心功能从Ⅲ~Ⅳ级改善为Ⅰ~Ⅲ级,左室射血分数由(26.42±6.7)%增加到(33.44±6.0)%,P<0.01;②左室舒张末内径由(75.31±8.52)mm减少至(67.24±10.57)mm,P<0.05;③左右室间收缩时间差、左室内不同步指数有显著改善,但随着术后时间的延长无明显变化。结论:CRT可以改善DCM患者的左、右室间和左室内收缩活动不同步,逆转心室扩大,提高心功能,其近期疗效显著。

关 键 词:心肌病  扩张型  心脏再同步化治疗  组织多普勒  起搏器参数  

Long-term outcome of cardic resynchronization therapy in the dilated cardiomyopathy patients
XU Maochun,QIU Jianping,ZHANG Yu,ZHU Hua,LIU Miao,SUN Minmin.Long-term outcome of cardic resynchronization therapy in the dilated cardiomyopathy patients[J].Journal of Clinical Cardiology,2010,26(2).
Authors:XU Maochun  QIU Jianping  ZHANG Yu  ZHU Hua  LIU Miao  SUN Minmin
Institution:1Department of Cardiology/a>;2Department of Echocardiography/a>;Shanghai Pudong New Area Gongli Hospital/a>;Shanghai/a>;200135/a>;China/a>;3Department of Echocardiography/a>;Shanghai Zhong-shan Hospital
Abstract:Objective:To investigate the long-term effect of cardiac resynchronization therapy (CRT) in patients with dilated cardiomyopathy.Method:Eighteen dilated cardiomyopathy patients with drug-refractory heartfailure received cardiac resynchronous pacing. Check all the patients using the two-dimensional echocardiography and Tissue Doppler imaging(TDI) before and one week after CRT. After 1 month,3 months,6 months and one year follow-up of patients with clinical symptoms,and compare the various parameters change. ...
Keywords:cardiomyopathy  dilated  cardiac resynchronization therapy  tissue Doppler imaging  pacemaker parameters  
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