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地塞米松对顺铂胸腔内注射治疗恶性胸腔积液的影响
引用本文:王秀勤,赵善良,刘佩英. 地塞米松对顺铂胸腔内注射治疗恶性胸腔积液的影响[J]. 齐鲁医学杂志, 2002, 17(4): 288-289
作者姓名:王秀勤  赵善良  刘佩英
作者单位:临沂市胸科医院,山东省临沂市,276034
摘    要:①目的 观察地塞米松对顺铂胸腔内注射治疗恶性胸腔积液效果的影响。②方法 将恶性胸腔积液病人 67例随机分为两组 ,对照组 37例 ,在常规治疗的基础上 ,给予顺铂 60mg +生理盐水 40mL ,地塞米松5mg +生理盐水 1 0mL ,在胸腔穿刺后注入胸腔内 ,每周 1次。治疗组 30例 ,除不用地塞米松外其余同对照组。③结果 治疗组第 1 ,2 ,3周疗效均优于对照组 (uc=3 .1 7,3 .0 8,2 .96 ,P <0 .0 1 )。④结论 地塞米松可降低顺铂胸腔内注射治疗恶性胸腔积液的效果

关 键 词:地塞米松 顺铂 胸腔内注射 治疗 恶性胸腔积液 影响
文章编号:1008-0341(2002)04-0288-02
修稿时间:2002-06-11

EFFECT OF DEXAMETHASONE OF THORACIC CAVITY CISPLATIN INJECTION ON MALIGNANT PLEURAL EFFUSION
WANG Xiuqin,ZHAO Shanliang,LIU Peiying Linyi Thoracic Hosptial,Linyi,Shandong. EFFECT OF DEXAMETHASONE OF THORACIC CAVITY CISPLATIN INJECTION ON MALIGNANT PLEURAL EFFUSION[J]. Medical Journal of Qilu, 2002, 17(4): 288-289
Authors:WANG Xiuqin  ZHAO Shanliang  LIU Peiying Linyi Thoracic Hosptial  Linyi  Shandong
Affiliation:WANG Xiuqin,ZHAO Shanliang,LIU Peiying Linyi Thoracic Hosptial,Linyi,Shandong 276034
Abstract:Objective To investigate the effect of dexamethasone of thoracic cavity injection on malignant pleural effusio n(MPE). Methods 67 patients with MPE were divided into two groups . 37 patients were treated with thoracic cavity cisplatin 60 mg+NS 40 mL injection and dexamethasone 5 mg+NS 10 mL injection after thoracocent sis once a week, as the control group; the other 30 patients were no t given dexamethasone, as the treated group. The two groups were tr eated simultaneously with the routine therapy. Results The curative effect of the treated group were bet ter than that of the control group ( u c=3.17, 3.08, 2.96,P <0.01). Conclusion Dexamethasone could reduce the curative effect of cisplatin on MPE. [
Keywords:cisplatin  dexamethasone  pleural effusion  trea tment outcome
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