浙江省1997至2000年肾综合征出血热监测分析

目的：通过对肾综合征出血热（HFRS）监测分析，掌握全省HFRS的流行规律，控制其暴发流行，进一步降低该病的发病率，为制定防制措施提供依据。方法：采用直接免疫荧光（FAT）法，检测鼠肺HV抗原，采用间接免疫荧光（IFAT）法检测HFRS病人，健康人血清及鼠血中HV抗体，结果：1997－2000年全省共发病9041例，年均发病率为5．08／10万，死亡48人，病死率为0．53％，病例仍主要分布在沿钱塘江两岸的浙东和浙西丘陵区，浙南山区次之，浙北平原区和海岛区病例较少，全省11个地市均有发病，以浙东和浙西丘陵区的绍兴，宁波，台洲，衢州，杭州和金华6市发病最多。宿主动物野外以黑线姬鼠为优势种，占80．79％，室内以褐家鼠为优势种，占80．91％，结论：需要进一步加大监测力度，同时接种HFRS疫苗。

Surveillance and Analysis of HFRS in Zhejiang Province from 1997 to 2000 Year

Objective: To study HFRS's prevalent regularity in the whole province,to control its outbreak and work out the way to deal with it.Methods: Direct Fluorescent Antibody Technic (FAT) was used to test HV antigen in rat's lung, Indirect Fluorescent Antibody Technic (IFAT) was used to test HV antibody in sera of patients and people in good health.Results: There were 9 041 patients in the whole province from 1997 to 2000, and 48 of them had died. The average morbidity was 5.08 per 100 000 persons. Most patients were in the east and west hilly land of Zhejiang province. 11 cities of Zhejiang province had patients. The patients were both disperse and relatively concentrately. Most patients came from Shaoxing, Ningbo, Taizhou, Quzhou, Hangzhou and Jinghua city. Main HFRS's host animal in field is Apodemus Agrarius Pallas, main host animal in house is Rattus Norvegicus Berkenhout. Conclusion: HFRS's surveil lance and vaccinated people with HFRS's vaccine should be enhanced.