Dominance of blaCTX-M within an Australian extended-spectrum beta-lactamase gene pool |
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| Authors: | Zong Zhiyong Partridge Sally R Thomas Lee Iredell Jonathan R |
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| Affiliation: | Centre for Infectious Diseases and Microbiology, University of Sydney, Sydney, New South Wales, Australia. |
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| Abstract: | ![]()
blaCTX-M genes, particularly blaCTX-M-15, are the dominant extended-spectrum β-lactamase (ESBL) genes among clinical isolates of Escherichia coli and Klebsiella pneumoniae in Sydney, Australia, where we also found one example of blaCTX-M-62, encoding a novel enzyme conferring ceftazidime resistance. ESBL genes were present in diverse community isolates and in a variety of associated conjugative plasmids. |
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