| 磺胺过敏患者使用磺脲类降糖药2例安全性分析 |
| |
| 引用本文： | 熊江红,王琳,邹慧琴,邓雪华,姚闽. 磺胺过敏患者使用磺脲类降糖药2例安全性分析[J]. 药品评价, 2021, 0(5): 285-288 |
| |
| 作者姓名： | 熊江红 王琳 邹慧琴 邓雪华 姚闽 |
| |
| 作者单位： | 江西省精神病院;南昌大学第一附属医院;江西省药品检验检测研究院 |
| |
| 摘 要： | 目的:探索磺胺过敏的患者使用磺脲类降糖药的安全性.方法:收集南昌大学第一附属医院2019年10月、11月收治的2例磺胺过敏患者使用磺脲类降糖药的病例,并查阅国内外相关文献.结果:被收集病例均未观察到过敏反应,各国在磺脲类药品说明书的标注差异较大.结论:考虑《磺脲类药物临床应用专家共识(2016年版)》提出磺胺过敏禁用,...
|
| 关 键 词： | 降血糖药 药物过敏 磺胺过敏 磺脲类降糖药 交叉过敏 2型糖尿病 药品说明书 |
Safety Analysis of Using Sulfonylurea Hypoglycemic Agents in 2 Patients with Sulfa Allergy |
| |
| XIONG Jianghong,WANG Lin,ZOU Huiqin,DENG Xuehua,YAO Min. Safety Analysis of Using Sulfonylurea Hypoglycemic Agents in 2 Patients with Sulfa Allergy[J]. Drug Evaluation, 2021, 0(5): 285-288 |
| |
| Authors: | XIONG Jianghong WANG Lin ZOU Huiqin DENG Xuehua YAO Min |
| |
| Affiliation: | (Jiangxi Psychiatric Hospital,Nanchang Jiangxi 330039,China;The First Affiliated Hospital of Nanchang University,Nanchang Jiangxi 330006,China;Jiangxi Provincial Institute for Drug Control,NMPA Key Laboratory of Quality Evaluation of Traditional Chinese Patent Medicine Jiangxi Provincial Engineering Research Center for Drug and Medical Device Quality,Nanchang Jiangxi 330029,China.) |
| |
| Abstract: | Objective:To assess the safety of sulfonylurea hypoglycemic drugs in patients with sulfa allergy.Methods:Collected two cases of sulfonamide allergy patients who were admitted to the First Affiliated Hospital of Nanchang University in October and November 2019,and reviewed relevant literature at home and abroad.Results:No anaphylaxis was observed in the collected cases.The labeling of sulfonylurea drug instructions varies greatly from country to country.Conclusion:Considering the"Consensus of Experts in Clinical Application of Sulfonylurea(2016 Edition)"that states sulfonylurea hypoglycemic drugs are contraindicated in patients with sulfa allergy,and following the principle of using the drug according to the instructions,it is recommended that medical personnel should use such drugs with caution in sulfonamide allergy patients.When it is difficult to avoid,sulfonylurea hypoglycemic drugs clearly mentioned as contraindications in patients with sulfa allergy in the instructions are not recommended as preferred choice;drugs not listed as contraindications in patients with sulfa allergy in the instructions should be judged based on the patients'previous response to sulfonamide antibacterial drugs. |
| |
| Keywords: | Hypoglycemic agents Drug hypersensitivity Sulfa allergy Sulfonylurea hypoglycemic agents Cross-allergy Type 2 diabetes Drug instructions |
| 本文献已被 维普 等数据库收录！ |
|
