曲美他嗪治疗老年顽固性心绞痛临床疗效观察 |
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引用本文: | 张卫国,Wei-guo. 曲美他嗪治疗老年顽固性心绞痛临床疗效观察[J]. 中原医刊, 2010, 0(4) |
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作者姓名: | 张卫国 Wei-guo |
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摘 要: | 目的 观察在强化治疗基础上加用曲美他嗪治疗老年顽固性心绞痛的疗效.方法 将65例老年顽固性心绞痛患者随机分为强化治疗组和联合治疗组,联合治疗组在强化治疗的基础上加用曲美他嗪20 mg,每日3次,疗程为4周.观察患者心绞痛发作次数、持续时间、心电图ST-T改变和硝酸酯类药物的用量.结果 联合治疗组患者总有效率为88.57%,与强化治疗组相比差异有统计学意义(P<0.05),两组间心绞痛发作次数与持续时间、硝酸酯类药物用量、心电图改善差异均有统计学意义(P<0.05).结论 治疗老年顽固性心绞痛,在强化治疗基础上加用曲美他嗪疗效安全可靠.Abstract:Objective To evaluate the effect of trimetazidine on elderly patients with refractory angina pectoris on the basis of intensive treatment. Methods Sixty - five patients with refractory angina pectoris were randomized into intensive treatment group and TMZ treatment group. In TMZ treatment group,TMZ(20 mg, 3 times per day) were given in addition to intensive treatment. The cycles of treatments in both groups were 4 weeks. The frequency and duration of angina attack, the ST - T segment change of electrocardiogram and the dosage of drugs belonging to ester nifrate were observed in patients with refractory angina pectoris. Results The total effective rate was 88.57% in TMZ group,and there was significant difference between the two groups ( P < 0. 05 ). With regard to the frequency and duration of angina attack,the dosage of drugs belonging to ester nitrate, the maximal ST - T segment depression, there were also significant differences between the two groups ( P <0. 05). Conclusions Combinating therapy of TMZ with intensive drugs have good curative effect for refractory angina pectoris, and is safe and reliable.
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关 键 词: | 曲美他嗪 强化治疗 老年 顽固性心绞痛 临床疗效观察 angina pectoris intensive treatment 治疗组 硝酸酯类药物 significant 统计学意义 治疗基础 发作次数 持续时间 elderly patients duration curative effect 心电图 患者 differences |
Therapeutic effect of trimetazidine on elderly patients with refractory angina pectoris |
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Abstract: | Rfractory angina pectoris Trimetazindine Eldely |
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Keywords: | Rfractory angina pectoris Trimetazindine Eldely |
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