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Moxibustion treatment increases the survival rate of lung infection of patients bed-ridden due to osteoporotic fracture of the spine via regulation of the inflammatory responses
Authors:Yaonan Cheng  Qin Chen  Ru Huang  Chunbo Lao  Wenbin Fu
Affiliation:1.Department of Acupuncture, Gaozhou Hospital of Traditional Chinese Medicine, Gaozhou, Guangdong, China;2.Department of Internal Medicine, Gaozhou Hospital of Traditional Chinese Medicine, Gaozhou, Guangdong, China;3.Department of Acupuncture, Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou, Guangdong, China
Abstract:IntroductionThis study aimed to investigate the potential role of moxibustion (MOX) in the treatment of lung infection in patients bed-ridden due to osteoporotic fracture of the spine.Methods96 senile patients with pulmonary infection who were bed-ridden due to osteoporotic fracture of the spine were grouped into a MOX (–) group and a MOX (+) group. An animal model was established as a SHAM group, a PRIMED group, a MOX 15’ group and a MOX 30’ group.ResultsFor the patients’ study, we found that the survival rate was higher for patients who received MOX. Moreover, tumor necrosis factor-α, interleukin (IL) 1β, IL-6 and IL-18 were down-regulated while IL-10 was up-regulated by MOX. MOX time-dependently increased the survival while reducing the bacteria left in infected mice.ConclusionsMoxibustion significantly alleviated the inflammatory responses, thus leading to a better survival rate of patients bed-ridden due to osteoporotic fracture of the spine.
Keywords:moxibustion   mice   bed-ridden senile   pulmonary infection   osteoporotic fracture
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