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RISK FACTORS FOR RECURRENCE IN PATIENTS WITH HEPATOCELLULAR CARCINOMA AFTER RADICAL RESECTION
引用本文:张博恒,周信达,余业勤,汤钊猷. RISK FACTORS FOR RECURRENCE IN PATIENTS WITH HEPATOCELLULAR CARCINOMA AFTER RADICAL RESECTION[J]. 中国癌症研究, 1994, 6(1): 58-62. DOI: 10.1007/BF02672263
作者姓名:张博恒  周信达  余业勤  汤钊猷
作者单位:Liver Cancer Institute,Shanghai Medical University,Shanghai 200032
摘    要:RISKFACTORSFORRECURRENCEINPATIENTSWITHHEPATOCELLULARCARCINOMAAFTERRADICALRESECTIONZhangBoheng张博恒ZhouXinda周信达YuYeqin余业勤TangZha...

收稿时间:1993-09-25

Risk factors for recurrence in patients with hepato-cellular carcinoma after radical resection
Zhang Boheng,Zhou Zinda,Yu Yeqin,Tang Zhaoyou. Risk factors for recurrence in patients with hepato-cellular carcinoma after radical resection[J]. Chinese Journal of Cancer Research, 1994, 6(1): 58-62. DOI: 10.1007/BF02672263
Authors:Zhang Boheng  Zhou Zinda  Yu Yeqin  Tang Zhaoyou
Affiliation:(1) Liver Cancer Institute, Shanghai Medical University, 200032 Shanghai
Abstract:Three hundred and eight patients with hepatocellular carcinoma underwent radical resection during 1975–1991. The 1-, 2-, 3-, 4-, 5-, and 10-year recurrent rates were 12.7%, 28.7%, 41.2%, 47.5%, 54.1% and 64.4% respectively. By the end of March 1992, recurrence had occurred in 134 patients. Risk factors for recurrence were analyzed. Cox univariate analysis identified the following five factors to be correlated with increasing risk: high γ-GT, discovery by clinical, macronodular cirrhosis, minor resection and portal vein embolus. However, only high γ-GT, macronodular cirrhosis, and minor resection have been proved significant risk factors for recurrence in Cox multivariate analysis. Larger hepatic resection might reduce recurrence, intra- andlor post- operation comprehensive treatments are adevocated.
Keywords:Hepatocellular carcinoma  Radical resection  Recurrence  Cox proportional-hazards model.
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