布地奈德、利多卡因联合雾化吸入治疗支气管哮喘的临床研究

目的探讨布地奈德、利多卡因联合雾化吸入治疗支气管哮喘的临床疗效。方法选择60例支气管哮喘患者随机分为对照组（30例）、治疗组（30例）,对照组采用传统基础治疗,以吸氧、抗炎,舒张支气管扩张等支持治疗,治疗组在对照组治疗的基础上加用布地奈德、利多卡因联合雾化吸入治疗,1个疗程结束后评定疗效。结果治疗组显效18例、有效6例、好转4例、无效2例,总有效率达93.3%;而对照组显效10例、有效7例、好转2例、无效11例,总有效率为63.3%,两组疗效经Ridit分析,治疗组疗效明显优于对照组（U=2.3553,P〈0.05）。结论在常规治疗的基础上采用布地奈德、利多卡因联合雾化吸入治疗支气管哮喘的方法疗效佳,而且安全性好,在临床上值得推广。

Clinical Research of Budesonide, Lidocaine Aerosol Inhalation in the Treatment of Bronchial Asthma

Objective To investigate the clinical effect of budesonide and lidocaine aerosol inhalation in the treatment of bronchial asthma.Methods Sixty patients with bronchial asthma were randomly divided into control group（30 cases） and treatment group（30 cases）.The control group received conventional basic treatment including oxygen,anti-inflammatory and aminophylline.The treatment group received the extra budesonide and lidocaine aerosol inhalation based on the conventional basic treatment.The therapeutic effect was evaluated after one treatment course.Results The total effective rate was 93.3% in the treatment group with 18 cases of excellence,6 cases of effectiveness,4 cases of improvement and 2 cases of ineffectiveness.The total effective rate was 63.3% in the control group with 10 cases of excellence,7 cases of effectiveness,2 cases of improvement and 11 cases of ineffectiveness.The result of Ridit analysis showed that the therapeutic effect in the treatment group was significantly superior to that in the control group（U = 2.3553,P 0.05）.Conclusions It is much better and safer to use budesonide and lidocaine aerosol inhalation based on the conventional basic treatment,which is worthy of clinical application.