子宫体中肾管腺癌一例并文献复习

中肾管腺癌是一种罕见的恶性肿瘤,来源于正常的中肾管残留组织或残留组织的过度增生,发病率低,多发生于宫颈,少见于子宫体。子宫体中肾管腺癌（UCMA）临床表现无特异性,主要为阴道出血,术前易被误诊为生殖道炎症、子宫肌瘤、宫颈癌和子宫内膜癌等。其确诊常依赖于细胞学、活检病理、免疫组织化学染色及和分子学特征,其中GATA3是中肾管腺癌特异性标志物。另外,UCMA预后较差,治疗方案常包括手术及辅助性放化疗。报告1例术前被误诊为子宫肌瘤的UCMA病例,并对相关文献进行复习,总结该病的临床特征,以期减少误诊,提高对本病的认识。

Mesonephric Adenocarcinoma of the Uterus Corpus: A Case Report and Literature Review

Mesonephric adenocarcinoma is a rare malignant tumor with a low incidence. It originates from mesonephric remnants or its hyperplasia, which often lies in cervix and rarely remains in the uterus corpus. Mesonephric adenocarcinoma of the uterus corpus(UCMA) is lack of special clinical presentation, which often presents with vaginal bleeding, thus leading to the diagnosis of genital tract inflammation, uterine fibroids, cervical cancer, endometrial cancer and so on. Cytology, pathology, immunohistochemistry and molecular character are required to get accurate diagnosis. According to recent reports, GATA3 is regarded as its special marker. In addition, the prognosis of UCMA is poor, and its treatment options include surgery and adjuvant radiotherapy and chemotherapy. This paper reports a case of UCMA that was misdiagnosed as uterine fibroids before surgery, reviews the relevant literature and summarized the clinical features in order to reduce its misdiagnosis and get awareness raised.