不同性别、临床科室患者血小板抗体筛查结果分析

目的 调查血小板抗体在住院患者中的阳性率,分析血小板抗体在性别之间的差异及在临床科室的分布情况,从而进一步保障临床患者输注血小板的有效性与安全性.方法 选取2019年3-5月在南京大学医学院附属鼓楼医院有输血可能的入院患者8 250例作为研究对象,采用固相凝集法检测其血小板抗体.计算抗体阳性率,并利用R3.4.1软件进...

Analysis of platelet antibody screening results in patients with different gender and clinical departments

Objective To investigate the positive rate of platelet antibody in hospitalized patients,analyze the difference of platelet antibody between genders and the distribution of clinical departments,so as to further ensure the effectiveness and safety of platelet transfusion in clinical patients.Methods A total of 8250 hospitalized patients with the possibility of blood transfusion in Gulou Hospital Affiliated to Medical College of Nanjing University from March to May 2019 were selected as the research objects,and their platelet antibodies were detected by solid phase agglutination method.The antibody positive rate was calculated and analyzed by R3.4.1 software.Results The positive rate of platelet antibody in female patients(6.6%)was significantly higher than that in male patients(4.43%),the difference was statistically significant(P<0.05).The results of cluster analysis showed that,the positive rate of antibody in rheumatology department,hematology department and traditional Chinese medicine department was significantly higher than that in other departments,the difference was statistically significant(P<0.05).Conclusion Female patients and patients with hematologic diseases and rheumatic immune diseases should pay attention to platelet antibody screening,so that positive patients can carry out platelet cross matching before platelet transfusion to avoid ineffective platelet transfusion.