基于Web of Science的耐多药结核文献计量分析

目的从文献计量学的角度反映了10年来耐多药结核研究的发展状况。方法利用SCIweb引文数据库检索1999—2008年间耐多药结核的文献，分别从耐多药结核研究的国家、机构和作者的发文量、被引频次和耐多药结核研究领域期刊分布情况及耐多药结核研究的学科主题等进行统计分析。结果统计范围内共有1521篇文献，分布于337种期刊，近5年来文献逐年增多。WHO、美国、比利时等在该领域的研究影响力比较大。耐多药结核病的研究主要集中在传染病学、呼吸系统疾病、微生物病原学、药物学等学科领域。结论由于耐多药结核病的流行对全球公共卫生安全产生重大威胁，耐多药结核病的研究逐渐引起各国的重视，中国作为耐多药结核病的高负担国家还有待提高对此项研究的投入和研究水平。

Bibliometric analysis of multidrug-resistant tuberculosis literatures in Web of Science

Objective To understand the progress in multidrug-resistant tuberculosis （MDR-TB） research over the last 10 years through a bibliometrie approach. Methods Literatures about MDR TB（1999--2008） were searched from Web of Science citation database. The searching results were analyzed concerning the article numbers and the frequency of citations by countries, institutes and authors, MDR-TB periodical distribution, and MDR-TB research subject distribution. Results Overall 1 521 papers were found and distributed in 337 types of periodicals. The number of papers has increased apparently over the last five years. World Health Organization, USA, Belgium have played important roles in the MDR-TB research in the world. The MDR-TB research subjects mostly focused on infectious diseases, respiratory diseases, microbiology, pharmacy and so on. Conclu- sions The prevalence of MDR-TB has been a threat to global public health security. This problem has attracted more and more attention. As a MDR-TB high-burden country, China should improve the level of investment and research on MDR-TB.