Successful treatment of earlobe keloids in the pediatric population |
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Authors: | Miller Hamrick William Boswell David Carney |
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Affiliation: | Department of Pediatric Surgery, Memorial Health University Medical Center, Savannah, GA 31406, USA |
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Abstract: |
BackgroundKeloid scars present a difficult treatment challenge. Recently, intralesional steroid injection has become a common treatment modality [Akoz et al. Aesthetic Plast Surg. 2002;6:184-188; Studdiford et al. JABFM. 2008;21:149-152]. Although this has become a proven treatment technique, there is no standard injection protocol to which treating physicians commonly adhere. We hypothesize that timing of steroid injection may improve outcomes using this treatment technique in combination with lesion excision.MethodsFifteen patients with 16 earlobe keloids were treated using a standard steroid injection protocol with Kenalog (Bristol-Myers Squibb, New York, NY), in combination with lesion excision. Strict follow-up was enforced, with repeat injections as needed at any sign of abnormal scar formation postoperatively.ResultsOf 16 lesions, 15 (94%) were treated successfully with no sign of lesion recurrence at 6 months of follow-up. A single lesion was lost to follow-up and presented 18 months postoperatively with recurrence. This lesion was subsequently retreated successfully.ConclusionsKenalog injection in combination with excision is a well-tolerated and effective treatment of earlobe keloids in the pediatric population. We feel that timing of injection and adherence to a strict follow-up regimen is crucial to success. |
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Keywords: | Keloid Kenalog Interferon alfa-2b Fibroblast Alpha1-antitrypsin Proteoglycans Hyaluronic acid Alpha-2-macroglobulin TGF-β bFGF |
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