首页 | 本学科首页   官方微博 | 高级检索  
     


Successful treatment of earlobe keloids in the pediatric population
Authors:Miller Hamrick  William Boswell  David Carney
Affiliation:Department of Pediatric Surgery, Memorial Health University Medical Center, Savannah, GA 31406, USA
Abstract:

Background

Keloid scars present a difficult treatment challenge. Recently, intralesional steroid injection has become a common treatment modality [Akoz et al. Aesthetic Plast Surg. 2002;6:184-188; Studdiford et al. JABFM. 2008;21:149-152]. Although this has become a proven treatment technique, there is no standard injection protocol to which treating physicians commonly adhere. We hypothesize that timing of steroid injection may improve outcomes using this treatment technique in combination with lesion excision.

Methods

Fifteen patients with 16 earlobe keloids were treated using a standard steroid injection protocol with Kenalog (Bristol-Myers Squibb, New York, NY), in combination with lesion excision. Strict follow-up was enforced, with repeat injections as needed at any sign of abnormal scar formation postoperatively.

Results

Of 16 lesions, 15 (94%) were treated successfully with no sign of lesion recurrence at 6 months of follow-up. A single lesion was lost to follow-up and presented 18 months postoperatively with recurrence. This lesion was subsequently retreated successfully.

Conclusions

Kenalog injection in combination with excision is a well-tolerated and effective treatment of earlobe keloids in the pediatric population. We feel that timing of injection and adherence to a strict follow-up regimen is crucial to success.
Keywords:Keloid   Kenalog   Interferon alfa-2b   Fibroblast   Alpha1-antitrypsin   Proteoglycans   Hyaluronic acid   Alpha-2-macroglobulin   TGF-β   bFGF
本文献已被 ScienceDirect 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号