首页 | 本学科首页   官方微博 | 高级检索  
     

乳腺癌彩色多普勒血流参数及血流丰富程度与淋巴结转移的相关性研究
引用本文:郭宁,杨漪. 乳腺癌彩色多普勒血流参数及血流丰富程度与淋巴结转移的相关性研究[J]. 中国医师进修杂志, 2011, 34(14). DOI: 10.3760/cma.j.issn.1673-4904.2011.14.004
作者姓名:郭宁  杨漪
作者单位:1. 首都医科大学附属北京同仁医院超声诊断科,100730
2. 河北医科大学第四医院超声科,石家庄,050011
基金项目:河北省卫生厅计划内课题
摘    要:
目的 探讨乳腺癌彩色多普勒血流参数及血流丰富程度与淋巴结转移的相关性.方法 将68例乳腺浸润性导管癌患者按有无淋巴结转移分为Ⅰ组(无淋巴结转移组,37例)和Ⅱ组(有淋巴结转移组,31例),Ⅱ组再根据淋巴结转移程度以胸小肌为标志分为Ⅱ a组(胸小肌外侧淋巴结转移组,19例)和Ⅱ b组(胸小肌后侧、锁骨下淋巴结转移组,12例).测量病灶的彩色多普勒血流参数[血流收缩期峰值流速(PSV)、血流阻力指数(RI)]及血流丰富程度(按Alder分级),比较其与淋巴结转移的关系.结果 Ⅰ组和Ⅱ组PSV、RI比较差异无统计学意义(t=-0.19、-0.63,P>0.05);Ⅱa组和Ⅱb组PSV、RI比较差异无统计学意义(t=-1.12、-0.13,P>0.05).Ⅰ组和Ⅱ组肿瘤血流丰富程度Alder分级比较差异无统计学意义(x2=0.46,P>0.05);Ⅱ a组Alder Ⅰ、Ⅱ、Ⅲ级分别占10.5%(2/19)、63.2%(12/19)、26.3%(5/19),Ⅱb组分别占8.3%(1/12)、16.7%(2/12)、75.0%(9/12),两组肿瘤血流丰富程度Alder分级比较差异有统计学意义(x2=7.41,P<0.05).结论 乳腺浸润性导管癌血流丰富程度与淋巴结转移有一定相关性;而乳腺癌彩色多普勒血流参数与淋巴结转移无显著相关性.
Abstract:
Objective To study the association among the color Doppler flow pattern, vascular distribution and the lymph nodes metastasis in breast carcinomas. Methods Sixty-eight patients with infiltrating mammary gland duct carcinoma were divided into the no-lymph-nodes-metastasis group (group I , 37 cases) and the lymph-nodes-metastasis group (group Ⅱ , 31 cases), group Ⅱ were subdivided into group Ⅱa (19 cases): lateral lymph nodes positive of pectoralis minor and group Ⅱ b (12 cases): rear of pectoralis minor and subclavian lymph node positive. Blood flow parameters [peak systoltc velocity (PSV),resistent index ( RI)] and vascular Alder grades were observed and measured with color Doppler ultrasound.The results were compared with the incidence of lymph node metastasis. Results PSV and RI were not significantly different between group Ⅰ and group Ⅱ (t = -0.19,-0.63,P> 0.05),and also between group Ⅱ a and group Ⅱ b (t =-1.12,-013,P >0.05). By using vascular Alder grades,there were no significant differences between group Ⅰ and group Ⅱ (x2= 0.46, P> 0.05 ), but the significant differences were observed between group Ⅱ a [10.5%(2/19) ,63.2%( 12/19) ,26.3%(5/19) in Alder Ⅰ , Ⅱ , Ⅲ grade] and group Ⅱ b [8.3%( 1/12), 16.7%(2/12),75.0%(9/12)in Alder Ⅰ , Ⅱ ,Ⅲ grade](x2 = 7.41,P<0.05). Conclusion The pattern of blood flow has no correlation with lymph nodes metastasis, vascular Alder grades of carcinoma shows some relevance with the lymph nodes metastasis in the patients with infiltrating mammary gland duct carcinoma.

关 键 词:癌,导管,乳腺  淋巴转移  超声检查,多普勒,彩色  血管Alder分级

Assessment of relationship among color Doppler flow pattern,vascular distribution and lymph nodes metastasis in breast carcinomas
GUO Ning,YANG Yi. Assessment of relationship among color Doppler flow pattern,vascular distribution and lymph nodes metastasis in breast carcinomas[J]. Chinese Journal of Postgraduates of Medicine, 2011, 34(14). DOI: 10.3760/cma.j.issn.1673-4904.2011.14.004
Authors:GUO Ning  YANG Yi
Abstract:
Objective To study the association among the color Doppler flow pattern, vascular distribution and the lymph nodes metastasis in breast carcinomas. Methods Sixty-eight patients with infiltrating mammary gland duct carcinoma were divided into the no-lymph-nodes-metastasis group (group I , 37 cases) and the lymph-nodes-metastasis group (group Ⅱ , 31 cases), group Ⅱ were subdivided into group Ⅱa (19 cases): lateral lymph nodes positive of pectoralis minor and group Ⅱ b (12 cases): rear of pectoralis minor and subclavian lymph node positive. Blood flow parameters [peak systoltc velocity (PSV),resistent index ( RI)] and vascular Alder grades were observed and measured with color Doppler ultrasound.The results were compared with the incidence of lymph node metastasis. Results PSV and RI were not significantly different between group Ⅰ and group Ⅱ (t = -0.19,-0.63,P> 0.05),and also between group Ⅱ a and group Ⅱ b (t =-1.12,-013,P >0.05). By using vascular Alder grades,there were no significant differences between group Ⅰ and group Ⅱ (x2= 0.46, P> 0.05 ), but the significant differences were observed between group Ⅱ a [10.5%(2/19) ,63.2%( 12/19) ,26.3%(5/19) in Alder Ⅰ , Ⅱ , Ⅲ grade] and group Ⅱ b [8.3%( 1/12), 16.7%(2/12),75.0%(9/12)in Alder Ⅰ , Ⅱ ,Ⅲ grade](x2 = 7.41,P<0.05). Conclusion The pattern of blood flow has no correlation with lymph nodes metastasis, vascular Alder grades of carcinoma shows some relevance with the lymph nodes metastasis in the patients with infiltrating mammary gland duct carcinoma.
Keywords:Carcinoma,ductal,breast  Lymphatic metastasis  Ultrasonography,Doppler,color  Vascular Aldergrade
本文献已被 万方数据 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号