低剂量薄层动态增强多排螺旋CT诊断乳腺癌的分析

 【摘要】　目的　使用受试者操作特征曲线（ROC曲线）分析探讨低剂量薄层动态增强多排螺旋CT（MDCT）在诊断乳腺癌方面的价值。方法　回顾性分析105例行64排MDCT检查并经病理证实的乳腺病变患者资料。其中采用常规剂量胸部CT检查参数的患者有48例，使用低剂量参数的患者57例。由两位具有5年以上临床经验的放射科医师对肿瘤影像学特征进行评估。以病理结果作为金标准，比较两组患者ROC曲线下面积（Az）的差异。结果　和常规剂量组相比，低剂量薄层动态增强MDCT对乳腺癌影像特征的显示效果能达到诊断要求，同时显著降低了照射剂量。结合动态增强特征，常规剂量组Az（0.943S）与低剂量组（0.908S）比较差异无统计学意义（t＝0.672，P＝0.324）。结论　低剂量薄层动态增强MDCT能有效安全地诊断乳腺癌。

Analysis of breast cancer using low-dose thin-thickness dynamic-enhanced MDCT

Objective To investigate the value of low-dose MDCT in the diagnosis of breast cancer using ROC analysis. Methods Retrospectively analyze the breast images of 105 cases that had performed both 64-row CT and pathological examinations. The case number that underwent CT examination with routinedose parameters was 48; and that with low-dose was 57. Two radiologists with clinical experiences more than 5 years evaluated the breast lesions, respectively. And ROC curve was used to test the diagnostic efficacy of breast cancer between the two groups. Results Compared with the routine-dose group, the quality of CT image was high enough to disclose the breast lesions while the exposure dose was significantly decreased. The areas under the ROC curve between the routine-dose group (0.943) and the low-dose group (0.908) did not show significant difference (P >0.05). Conclusion Low-dose thin-slice MDCT with contrast enhancement can efficiently and safely diagnose breast cancer.